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MIRAGE

Inositol polyphosphate 1-phosphatase

Summary

UniProt ID: P49442
Gene Symbol: Inpp1
Gene ID: 16329
Organism: Mus musculus (house mouse)

External Links

GlyGen: P49442
PubChem: P49442
The O-GlcNAc Database: P49442
O-GlcNAcAtlas: P49442
Re-Glyco: P49442

Annotation

Keyword: Hydrolase Lithium Magnesium Metal-binding Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	Reference
phosphatidylinositol phosphate biosynthetic process	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylinositol phosphate biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	Reference
inositol-1,4-bisphosphate 1-phosphatase activity	ISS	GO_REF
inositol-1,4-bisphosphate 1-phosphatase activity	IBA	GO_REF
inositol-1,4-bisphosphate 1-phosphatase activity	IEA	GO_REF GO_REF
metal ion binding
inositol-1,3,4-trisphosphate 1-phosphatase activity	ISS	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

inositol phosphate phosphatase activity [inference]

inositol bisphosphate phosphatase activity [inference]

inositol-1,4-bisphosphate 1-phosphatase activity

inositol trisphosphate phosphatase activity [inference]

inositol-1,3,4-trisphosphate 1-phosphatase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSDILLELLCVSEKAANIARACRQQETLFQLLIEEKKGAEKNKKFAADFKTLADVLVQEVIKQNMENKFPGLGKKVFGEESNEFTNDLGEKITVELQSTEEETAELLSKVLNGNMPASEALAQVVHEDVDLTDPTLESLDISIPHESLGIWVDPIDSTYQYIKGSANVKSNQGIFPSGLQCVTILIGVYDLQTGLPLMGVINQPFASQNLTTLRWKGQCYWGLSYMGTNIHSLQLAISKSDSETQTENSDREFSSPFSAVISTSEKDTIKAALSRVCGGSVFPAAGAGYKSLCVIQGLADIYIFSEDTTYKWDSCAAHAILRAMGGGIVDMKECLERSPDTGLDLPQLLYHVENKGASGVELWANKGGLIAYRSRNRLDTFLSRLIQNLGPVKTQA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
394		22645316 33300544 35822049 37507081 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Synthesis of IP2, IP, and Ins in the cytosol	Mus musculus

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026