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ADP/ATP translocase 2

Summary

UniProt ID: P51881
Gene Symbol: Aac2 Ant2 Slc25a5
Gene ID: 11740
Organism: Mus musculus (house mouse)

External Links

GlyGen: P51881
PubChem: P51881
RaftProt: P51881
O-GlcNAcAtlas: P51881
Re-Glyco: P51881

Annotation

Keyword: ATP-binding Acetylation Antiport Chromosome partition Direct protein sequencing Methylation Mitochondrion inner membrane Phosphoprotein Reference proteome Repeat Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	Reference
chromosome segregation
positive regulation of cell population proliferation	ISS	GO_REF
positive regulation of cell population proliferation	ISO	GO_REF
positive regulation of cell population proliferation	IEA	GO_REF
B cell differentiation	IMP	PMID

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

cell cycle process [inference]

chromosome segregation

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

myeloid cell differentiation [inference]

erythrocyte differentiation

transmembrane transport [inference]

purine-containing compound transmembrane transport [inference]

nucleotide transmembrane transport [inference]

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

adaptive thermogenesis

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

myeloid cell differentiation [inference]

erythrocyte differentiation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

adaptive thermogenesis

response to stimulus [inference]

response to chemical [inference]

response to peptide [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

localization [inference]

establishment of localization [inference]

transport [inference]

organic anion transport [inference]

ADP transport [inference]

mitochondrial ADP transmembrane transport

ATP transport [inference]

mitochondrial ATP transmembrane transport

organophosphate ester transport [inference]

nucleotide transport [inference]

purine nucleotide transport [inference]

purine ribonucleotide transport [inference]

ADP transport [inference]

mitochondrial ADP transmembrane transport

ATP transport [inference]

mitochondrial ATP transmembrane transport

adenine nucleotide transport

ADP transport [inference]

mitochondrial ADP transmembrane transport

ATP transport [inference]

mitochondrial ATP transmembrane transport

nucleotide transmembrane transport [inference]

transmembrane transport [inference]

purine-containing compound transmembrane transport [inference]

nucleotide transmembrane transport [inference]

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

purine nucleotide transport [inference]

purine ribonucleotide transport [inference]

ADP transport [inference]

mitochondrial ADP transmembrane transport

ATP transport [inference]

mitochondrial ATP transmembrane transport

adenine nucleotide transport

ADP transport [inference]

mitochondrial ADP transmembrane transport

ATP transport [inference]

mitochondrial ATP transmembrane transport

nucleotide transmembrane transport [inference]

purine-containing compound transmembrane transport [inference]

carbohydrate derivative transport [inference]

purine ribonucleotide transport [inference]

ADP transport [inference]

mitochondrial ADP transmembrane transport

ATP transport [inference]

mitochondrial ATP transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

regulation of autophagy [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

regulation of macroautophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

regulation of mitophagy [inference]

positive regulation of mitophagy

regulation of autophagy of mitochondrion [inference]

regulation of mitophagy [inference]

positive regulation of mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of autophagy [inference]

positive regulation of macroautophagy [inference]

positive regulation of mitophagy

positive regulation of autophagy of mitochondrion [inference]

positive regulation of mitophagy

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of mitochondrion organization [inference]

regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of biological quality [inference]

regulation of membrane permeability [inference]

regulation of mitochondrial membrane permeability

negative regulation of mitochondrial membrane permeability [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

negative regulation of membrane permeability [inference]

negative regulation of mitochondrial membrane permeability [inference]

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	Reference
mitochondrion	ISO	GO_REF
mitochondrion	IEA	GO_REF
mitochondrion	HDA	PMID PMID
mitochondrial inner membrane	ISS	GO_REF
mitochondrial inner membrane	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

MMXD complex

membrane protein complex [inference]

pore complex [inference]

mitochondrial permeability transition pore complex

mitochondrial protein-containing complex [inference]

mitochondrial permeability transition pore complex

cellular anatomical structure [inference]

nucleoid [inference]

mitochondrial nucleoid

membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

membrane microdomain [inference]

membrane raft

myelin sheath

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

membraneless organelle [inference]

intracellular membraneless organelle [inference]

mitochondrial nucleoid

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular membraneless organelle [inference]

mitochondrial nucleoid

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
adenine nucleotide transmembrane transporter activity	ISO	GO_REF
adenine nucleotide transmembrane transporter activity	IEA	GO_REF
ATP:ADP antiporter activity	IDA	PMID
ATP:ADP antiporter activity	IMP	PMID
ATP:ADP antiporter activity	IEA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity

organophosphate ester transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

purine nucleotide transmembrane transporter activity [inference]

adenine nucleotide transmembrane transporter activity

ATP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

ADP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

purine ribonucleotide transmembrane transporter activity [inference]

ATP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

ADP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

nucleobase-containing compound transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

purine nucleotide transmembrane transporter activity [inference]

adenine nucleotide transmembrane transporter activity

ATP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

ADP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

purine ribonucleotide transmembrane transporter activity [inference]

ATP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

ADP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

oxidative phosphorylation uncoupler activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity [inference]

ATP:ADP antiporter activity

carbohydrate derivative transmembrane transporter activity [inference]

purine ribonucleotide transmembrane transporter activity [inference]

ATP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

ADP transmembrane transporter activity [inference]

ATP:ADP antiporter activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGSKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites