GlyCosmos Portal

Pancreatic lipase-related protein 2

Summary

UniProt ID: P54317
Gene Symbol: PNLIPRP2 PLRP2
Gene ID: 5408
Organism: Homo sapiens (human)

External Links

GlyGen

P54317

PubChem

P54317

SwissLipids

SLP:000001434

The Human Metabolome Database

HMDBP00245

Re-Glyco

P54317

Annotation

Keyword: 3D-structure Calcium Cell projection Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Lipid degradation Membrane Metal-binding Proteomics identification Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
fatty acid biosynthetic process	IBA	GO_REF
triglyceride metabolic process	TAS	PMID
phospholipid catabolic process	IDA	PMID
phospholipid catabolic process	IBA	GO_REF
galactolipid catabolic process	IDA	PMID PMID PMID PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

catabolic process [inference]

lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

triglyceride catabolic process

acylglycerol catabolic process [inference]

triglyceride catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

lipid biosynthetic process [inference]

fatty acid biosynthetic process

lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

triglyceride catabolic process

acylglycerol catabolic process [inference]

triglyceride catabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

triglyceride catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

galactolipid metabolic process [inference]

galactolipid catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

galactolipid metabolic process [inference]

galactolipid catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

multicellular organismal process [inference]

digestion [inference]

lipid digestion

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
extracellular region	EXP	PMID
extracellular region	TAS	PMID Reactome
extracellular region	IDA	PMID
extracellular region	IEA	GO_REF
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

zymogen granule membrane

bounding membrane of organelle [inference]

secretory granule membrane [inference]

zymogen granule membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
lipoprotein lipase activity	IBA	GO_REF
glycerophospholipase activity	IDA	PMID PMID
triacylglycerol lipase activity	ISS	GO_REF
triacylglycerol lipase activity	EXP	PMID PMID PMID PMID PMID
triacylglycerol lipase activity	TAS	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

triacylglycerol lipase activity

lipoprotein lipase activity

phospholipase activity [inference]

glycerophospholipase activity

A1-type glycerophospholipase activity [inference]

glycerophospholipid phospholipase A1 activity

carboxylic ester hydrolase activity [inference]

triacylglycerol lipase activity

lipoprotein lipase activity

A1-type glycerophospholipase activity [inference]

glycerophospholipid phospholipase A1 activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLPPWTLGLLLLATVRGKEVCYGQLGCFSDEKPWAGTLQRPVKLLPWSPEDIDTRFLLYTNENPNNFQLITGTEPDTIEASNFQLDRKTRFIIHGFLDKAEDSWPSDMCKKMFEVEKVNCICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVHVIGHSLGAHTAAEAGRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPIVPSLGFGMSQKVGHLDFFPNGGKEMPGCKKNVLSTITDIDGIWEGIGGFVSCNHLRSFEYYSSSVLNPDGFLGYPCASYDEFQESKCFPCPAEGCPKMGHYADQFKGKTSAVEQTFFLNTGESGNFTSWRYKISVTLSGKEKVNGYIRIALYGSNENSKQYEIFKGSLKPDASHTCAIDVDFNVGKIQKVKFLWNKRGINLSEPKLGASQITVQSGEDGTEYNFCSSDTVEENVLQSLYPC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
353	N-linked (GlcNAc...) asparagine	18702514		UniProt GlyGen
428	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Developmental Lineage of Pancreatic Acinar Cells	Homo sapiens
Digestion of dietary lipid	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements