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MIRAGE
Hydroxymethylglutaryl-CoA synthase, mitochondrial
Summary
- UniProt ID
- P54869
- Gene Symbol
- Hmgcs2
- Gene ID
- 15360
- Organism
- Mus musculus (house mouse)
External Links
- GlyGen
- P54869
- PubChem
- P54869
- The Human Metabolome Database
- HMDBP13609
- O-GlcNAcAtlas
- P54869
- Re-Glyco
- P54869
Annotation
- Keyword
- Acetylation Cholesterol biosynthesis Mitochondrion Phosphoprotein Reference proteome Transferase Transit peptide
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| kidney development | ||
| liver development | ||
| acetyl-CoA metabolic process | ||
| acetyl-CoA metabolic process | ||
| acetyl-CoA metabolic process |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| mitochondrion | ||
| mitochondrion | ||
| mitochondrion | ||
| mitochondrion | ||
| mitochondrion |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| hydroxymethylglutaryl-CoA synthase activity | ||
| hydroxymethylglutaryl-CoA synthase activity | ||
| hydroxymethylglutaryl-CoA synthase activity | ||
| hydroxymethylglutaryl-CoA synthase activity | ||
| identical protein binding |
GO Hierarchy
Sequence
MQRLLAPARRVLQVKRAMQETSLTPAHLLSAAQQRFSTIPPAPLAKTDTWPKDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLVLEQGLRGTHMENAYDFYKPNLASEYPLVDGKLSIQCYLRALDRCYAAYRKKIQNQWKQAGNNQPFTLDDVQYMIFHTPFCKMVQKSLARLMFNDFLSSSSDKQNNLYKGLEAFRGLKLEETYTNKDVDKALLKASLDMFNQKTKASLYLSTNNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASFFSFRVSKDASPGSPLEKLVSSVSDLPKRLDSRRRMSPEEFTEIMNQREQFYHKVNFSPPGDTSNLFPGTWYLERVDEMHRRKYARCPV
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Mitochondrial protein degradation | Mus musculus |
| Synthesis of Ketone Bodies | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081168 | HMG-CoA synthase 2 deficiency |
