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Sodium channel regulatory subunit beta-2

Summary

UniProt ID: P54900
Gene Symbol: Scn2b
Gene ID: 25349
Organism: Rattus norvegicus (Norway rat)

External Links

PubChem: P54900
Re-Glyco: P54900

Annotation

Keyword: Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Phosphoprotein Reference proteome Signal Sodium transport Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	Reference
sodium ion transport	ISO	GO_REF
nervous system development	IEP	PMID
response to heat	ISO	GO_REF
gene expression	ISO	GO_REF
positive regulation of sodium ion transport	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction [inference]

cardiac muscle contraction

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

response to stimulus [inference]

response to stress [inference]

response to heat

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

response to chemical [inference]

response to toxic substance [inference]

response to insecticide [inference]

response to pyrethroid

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

positive regulation of sodium ion transport

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport

regulation of cellular process [inference]

regulation of membrane depolarization [inference]

regulation of atrial cardiac muscle cell membrane depolarization

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

cardiac conduction

regulation of heart rate by cardiac conduction

regulation of biological quality [inference]

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

regulation of membrane potential [inference]

action potential [inference]

cardiac muscle cell action potential [inference]

cardiac muscle cell action potential involved in contraction

regulation of membrane depolarization [inference]

regulation of atrial cardiac muscle cell membrane depolarization

membrane depolarization [inference]

membrane depolarization during action potential

membrane depolarization during cardiac muscle cell action potential

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
voltage-gated sodium channel complex	ISS	GO_REF
voltage-gated sodium channel complex	ISO	GO_REF
voltage-gated sodium channel complex	TAS	PMID
voltage-gated sodium channel complex	IBA	GO_REF
voltage-gated sodium channel complex	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated sodium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

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GO Term	Evidence Code	Reference
voltage-gated sodium channel activity	IDA	PMID
sodium channel regulator activity	ISO	GO_REF
sodium channel regulator activity	IDA	PMID
sodium channel regulator activity	IBA	GO_REF
sodium channel regulator activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

sodium channel activity [inference]

voltage-gated sodium channel activity

voltage-gated sodium channel activity involved in cardiac muscle cell action potential

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

sodium channel activity [inference]

voltage-gated sodium channel activity

voltage-gated sodium channel activity involved in cardiac muscle cell action potential

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

voltage-gated sodium channel activity

voltage-gated sodium channel activity involved in cardiac muscle cell action potential

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

sodium channel activity [inference]

voltage-gated sodium channel activity

voltage-gated sodium channel activity involved in cardiac muscle cell action potential

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

sodium channel regulator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MHRDAWLPRPAFSLTGLSLFFSLVPSGRSMEVTVPTTLSVLNGSDTRLPCTFNSCYTVNHKQFSLNWTYQECSNCSEEMFLQFRMKIINLKLERFGDRVEFSGNPSKYDVSVTLKNVQLEDEGIYNCYITNPPDRHRGHGKIYLQVLLEVPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNAEDGAK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites