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182 kDa tankyrase-1-binding protein

Summary

UniProt ID: P58871
Gene Symbol: Kiaa1741 Tab182 Tnks1bp1
Gene ID: 228140
Organism: Mus musculus (house mouse)

External Links

GlyGen: P58871
PubChem: P58871
The O-GlcNAc Database: P58871
O-GlcNAcAtlas: P58871
Re-Glyco: P58871

Annotation

Keyword: ADP-ribosylation Chromosome Cytoskeleton Methylation Nucleus Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
double-strand break repair	ISO	GO_REF
double-strand break repair	IBA	GO_REF
double-strand break repair	IEA	GO_REF
cellular response to ionizing radiation	ISO	GO_REF
cellular response to ionizing radiation	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

double-strand break repair

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

double-strand break repair

response to abiotic stimulus [inference]

response to radiation [inference]

response to ionizing radiation [inference]

cellular response to ionizing radiation

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

double-strand break repair

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
heterochromatin	ISO	GO_REF
heterochromatin	IBA	GO_REF
heterochromatin	IEA	GO_REF
nucleus	ISS	GO_REF
nucleus	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

CCR4-NOT complex

cellular anatomical structure [inference]

chromatin [inference]

heterochromatin

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

cytoskeleton

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
enzyme binding	ISO	GO_REF
enzyme binding	IEA	GO_REF
protein serine/threonine kinase activator activity	ISO	GO_REF
protein serine/threonine kinase activator activity	IEA	GO_REF
protein-containing complex binding	ISO	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding

protein domain specific binding [inference]

ankyrin repeat binding

protein-containing complex binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKGSTLREGTAMASPLPQDMEEELAPVGSEPGDPRAKPPVKPKPRGLPSKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGVSKRPLPFAPRPSAEATAGGDVTQESGKEDAGKEDLPPLTPPARCAALGGVRKAPAPFRPSSERFAACTVEEILAKMEQPRKEILASPDRLWGSRLTFNHDGSSRYGPRTYGAPCPREEDSKSPAKGRSQEGTAEIPAECQEEHSKTPEERNLTSSPAMNGDLAKLACSEAPTDVSKTWVTSSADPVSEHGGSTSAVRLANISVPASESPRLSSRPSSPCHSQLSETQSPAASEASSICLPVTPASPSAVLPAEPPGHSPSSELPAEAAPETLSPNSSPVETVSGHHSPEQPPVLLPQLLTEGAELPDITRTFPCGEEAAARGHTESRPSSLAQRRFSEGVLQPPSQDQEKLGGSLATLPQGQGSQSALDRPFGSGTESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEADSWAVSGRGEGVSQVGPGTPPAPESPRKPISGVQGNDPGISLPQRDDGESQPRSPALLPSTVEGPPGAPLLQAKENYEDQEPLVGHESPITLAAREAALPVLEPALGQQQPTPSDQPCILFVDVPDPEQALSTEEDVVTLGWAETTLPMTEAQEPCSVSPEPTGPESSSRWLDDLLASPPPNSGSARRAAGAELKDRQSPSTCSEGLLGWAQKDLQSEFGVATDSHHSSFGSSSWSQDTSQNYSLGGRSPVGDTGLGKRDWSSKCGQGSGEGSTREWASRHSLGQEVIGIGGSQDESEVPVRERAVGRPAQLGAQGLEADAQQWEFGKRESQDPHSIHDKELQDQEFGKRDSLGSFSTRDASLQDWEFGKRASVSTNQDTDENDQELGMKNLSRGYSSQDAEEQDREFEKRDSVLDIHGSRATAQQNQEFGKSAWFQDYSSGGGGSRVLGSQERGFGIRSLSSGFSPEEAQQQDEEFEKKTPVGEDRFCEASRDVGHLEEGASGGLLSPSTPHSRDGAARPKDEGSWQDGDSSQEITRLQGRMQAESQSPTNVDLEDKEREQRGWAGEFSLGVAAQSEAAFSPGRQDWSRDVCVEASESSYQFGIIGNDRVSGAGLSPSRKSGGGHFVPPGETKAGAVDWTDQLGLRNLEVSSCVSSEGPSEARENVVGQMGWSDSLGLNNGDLARRLGTGESEEPRSLGVGEKDWTSSVEARNRDLPGQAEVGRHSQARESGVGEPDWSGAEAGEFLKSRERGVGQADWTPDLGLRNMAPGAGCSPGEPRELGVGQVDWGDDLGLRNLEVSCDLESGGSRGCGVGQMDWAQDLGLRNLRLCGAPSEVRECGVGRVGPDLELDPKSSGSLSPGLETEDPLEARELGVGEISGPETQGEDSSSPSFETPSEDTGMDTGEAPSLGASPSSCLTRSPPSGSQSLLEGIMTASSSKGAPQRESAASGSRVLLEEEGLAAGAGQGEPQEPSRAPLPSSRPQPDGEASQVEEVDGTWSLTGAARQNEQASAPPPRRPPRGLLPSCPSEDFSFIEDTEILDSAMYRSRANLGRKRGHRAPAIRPGGTLGLSETADSDTRLFQDSTEPRASRVPSSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRSRNRSAEEGEVTESKSSQKESSVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	PubMed ID	GlyTouCan ID	Source
243		G85269DF	GlyGen
260	21540332 22517741 22645316 25153642 26192747 28135057 28528544 29562282 30059200 34678516 35822049 36852467 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database
267	21540332 22517741 22645316 25153642 26192747 28135057 28528544 29562282 30059200 34678516 35822049 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database
269		G49108TO	GlyGen
334			GlyGen
626			GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Deadenylation of mRNA	Mus musculus
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements