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Phospholipid phosphatase 1

Summary

UniProt ID: P60588
Gene Symbol: LPP1 PLPP1 PPAP2A
Gene ID: 100515451
Organism: Sus scrofa (pig)

External Links

PubChem: P60588
Re-Glyco: P60588

Annotation

Keyword: Cell membrane Direct protein sequencing Glycoprotein Hydrolase Lipid metabolism Reference proteome Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
phospholipid metabolic process	IBA	GO_REF
phospholipid metabolic process	IEA	GO_REF GO_REF GO_REF
sphingosine metabolic process	ISS	GO_REF
ceramide metabolic process	ISS	GO_REF
signal transduction	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

phospholipid catabolic process

dephosphorylation [inference]

phospholipid dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process

phospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

catabolic process [inference]

lipid catabolic process [inference]

phospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process

phospholipid catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process

sphingoid metabolic process [inference]

sphingosine metabolic process

lipid catabolic process [inference]

phospholipid catabolic process

lipid modification [inference]

phospholipid dephosphorylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

sphingosine metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

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GO Term	Evidence Code	Reference
plasma membrane	IDA	PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
caveola	ISS	GO_REF
caveola	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft

plasma membrane raft [inference]

caveola

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GO Term	Evidence Code	Reference
diacylglycerol diphosphate phosphatase activity	ISS	GO_REF
diacylglycerol diphosphate phosphatase activity	IEA	GO_REF GO_REF
phosphatidate phosphatase activity	IDA	PMID PMID
phosphatidate phosphatase activity	IEA	GO_REF GO_REF GO_REF
sphingosine-1-phosphate phosphatase activity	ISS	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

lipid phosphatase activity [inference]

lysophosphatidic acid phosphatase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

diacylglycerol diphosphate phosphatase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MFDKTRLPYVALDVLCVLLAGLPFAILTSRHTPFQRGLFCNDESIKYPYKEDTIPYPLLGGIIIPFSIIVMIVGETLSVYFNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIENYICRGNAQKVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAIVVAVYVSDFFKERNSPFKERKEEDSHTTLHETPTTGNHYRNSHQP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
142	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Sphingolipid catabolism	Sus scrofa

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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International Collaboration

Acknowledgements