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D(2) dopamine receptor

Summary

UniProt ID

P61169

Gene Symbol

Drd2

Gene ID

24318

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P61169
Re-Glyco: P61169

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Golgi apparatus
Palmitate
Reference proteome
Transmembrane helix

Gene Ontology (GO)

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GO Term
plasma membrane
cilium
membrane
axon
dendrite
postsynaptic membrane
presynapse
Golgi membrane
endocytic vesicle
acrosomal vesicle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
G protein-coupled receptor signaling pathway
neuron-neuron synaptic transmission
visual learning
response to xenobiotic stimulus
intracellular potassium ion homeostasis
response to estradiol
circadian regulation of gene expression
positive regulation of multicellular organism growth
response to cocaine
positive regulation of MAPK cascade

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GO Term
G protein-coupled receptor activity
identical protein binding
protein-containing complex binding
dopamine neurotransmitter receptor activity, coupled via Gi/Go
G-protein alpha-subunit binding
dopamine neurotransmitter receptor activity
ionotropic glutamate receptor binding
organic cyclic compound binding
heterocyclic compound binding
signaling receptor binding

Annotation information from UniProt.

Sequence

MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
5	N-linked (GlcNAc...) asparagine	UniProt
17	N-linked (GlcNAc...) asparagine	UniProt
23	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Dopamine receptors	Rattus norvegicus

Disease

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050696	fetal alcohol spectrum disorder	Alliance of Genome Resources
DOID:0080855	Parkinsonism	Alliance of Genome Resources
DOID:5425	ovarian hyperstimulation syndrome	Alliance of Genome Resources
DOID:9975	cocaine dependence	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements