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MIRAGE
14-3-3 protein epsilon
Summary
- UniProt ID
- P62259
- Gene Symbol
- Ywhae
- Gene ID
- 22627
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| MAPK cascade | ||
| MAPK cascade | ||
| MAPK cascade | ||
| neuron migration | ||
| neuron migration |
GO Hierarchy
- regulation of membrane repolarization
biological process
immune system process [inference]
cellular process [inference]
homeostatic process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein phosphatase inhibitor activity | ||
| calcium channel regulator activity | ||
| calcium channel regulator activity | ||
| potassium channel regulator activity | ||
| potassium channel regulator activity |
Sequence
MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEEQNKEALQDVEDENQ
Glycosylation Sites
G49642SA
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AURKA Activation by TPX2 | Mus musculus |
| Activation of BAD and translocation to mitochondria | Mus musculus |
| Anchoring of the basal body to the plasma membrane | Mus musculus |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | Mus musculus |
| HSF1 activation | Mus musculus |
| Loss of Nlp from mitotic centrosomes | Mus musculus |
| Loss of proteins required for interphase microtubule organization from the centrosome | Mus musculus |
| NADE modulates death signalling | Mus musculus |
| RAB GEFs exchange GTP for GDP on RABs | Mus musculus |
| RHO GTPases activate PKNs | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060480 | left ventricular noncompaction | |
| DOID:0060469 | Miller-Dieker lissencephaly syndrome |
