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Mitogen-activated protein kinase 1

Summary

UniProt ID

P63086

Gene Symbol

Mapk1
Erk2
Mapk
Prkm1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P63086
PubChem: P63086
The O-GlcNAc Database: P63086

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Apoptosis
Cell cycle
Cell junction
Cytoskeleton
Direct protein sequencing
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
outer ear morphogenesis
myelination
negative regulation of cell differentiation
positive regulation of translation
thymus development
regulation of cytoskeleton organization
Bergmann glial cell differentiation
positive regulation of cardiac muscle cell proliferation
face development
lung morphogenesis

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GO Term
mitochondrion
cytosol
caveola
nucleoplasm
centrosome
early endosome
late endosome
focal adhesion
postsynaptic density
plasma membrane

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GO Term
protein kinase activity
protein serine/threonine kinase activity
kinase activity
protein kinase binding
mitogen-activated protein kinase kinase kinase binding
identical protein binding
double-stranded DNA binding
phosphatase binding
phosphotyrosine residue binding
MAP kinase activity

Annotation information from UniProt.

Sequence

MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **31 - 40** of 44 in total

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Pathway Name	Organism
Recycling pathway of L1	Rattus norvegicus
Regulation of HSF1-mediated heat shock response	Rattus norvegicus
Regulation of actin dynamics for phagocytic cup formation	Rattus norvegicus
Regulation of the apoptosome activity	Rattus norvegicus
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Rattus norvegicus
Senescence-Associated Secretory Phenotype (SASP)	Rattus norvegicus
Signal attenuation	Rattus norvegicus
Signal transduction by L1	Rattus norvegicus
Signaling by Activin	Rattus norvegicus
Signaling by NODAL	Rattus norvegicus