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Potassium voltage-gated channel subfamily A member 2

Summary

UniProt ID

P63141

Gene Symbol

Kcna2

Gene ID

16490

Organism

Mus musculus (house mouse)

External Links

GlyGen: P63141
PubChem: P63141
The O-GlcNAc Database: P63141
O-GlcNAcAtlas: P63141
Re-Glyco: P63141

Annotation

Keyword: 3D-structure Cell junction Cell membrane Cell projection Endoplasmic reticulum Glycoprotein Palmitate Phosphoprotein Potassium channel Reference proteome Synaptosome Transmembrane helix Voltage-gated channel

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
action potential	IBA	GO_REF
regulation of dopamine secretion	IMP	PMID
neuronal action potential	ISS	GO_REF
neuronal action potential	ISO	GO_REF
neuronal action potential	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion export across plasma membrane

export across plasma membrane [inference]

potassium ion export across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

export from cell [inference]

export across plasma membrane [inference]

potassium ion export across plasma membrane

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of pain

developmental process [inference]

anatomical structure arrangement [inference]

cranial nerve structural organization [inference]

optic nerve structural organization

anatomical structure development [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

potassium ion export across plasma membrane

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion export across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion export across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion export across plasma membrane

export across plasma membrane [inference]

potassium ion export across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

potassium ion export across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of catecholamine secretion [inference]

regulation of dopamine secretion

regulation of amine transport [inference]

regulation of catecholamine secretion [inference]

regulation of dopamine secretion

regulation of circadian rhythm [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

regulation of circadian sleep/wake cycle, non-REM sleep

regulation of cellular process [inference]

regulation of secretion by cell [inference]

regulation of catecholamine secretion [inference]

regulation of dopamine secretion

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

regulation of circadian sleep/wake cycle, non-REM sleep

regulation of biological quality [inference]

regulation of membrane potential [inference]

action potential

neuronal action potential

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GO Term	Evidence Code	Reference
endoplasmic reticulum membrane	ISO	GO_REF
endoplasmic reticulum membrane	IEA	GO_REF
plasma membrane	ISO	GO_REF GO_REF
plasma membrane	EXP	PMID PMID PMID PMID
plasma membrane	IMP	PMID PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex

voltage-gated potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex

voltage-gated potassium channel complex

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

plasma membrane region [inference]

cell projection membrane [inference]

lamellipodium membrane

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-cell junction [inference]

paranodal junction

leading edge membrane [inference]

lamellipodium membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

neuron projection [inference]

cell body membrane [inference]

neuronal cell body membrane

neuron projection terminus [inference]

axon terminus

calyx of Held

presynapse [inference]

axon terminus

calyx of Held

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	Reference
voltage-gated potassium channel activity	ISO	GO_REF GO_REF
voltage-gated potassium channel activity	IDA	PMID PMID PMID PMID PMID PMID
voltage-gated potassium channel activity	IMP	PMID
voltage-gated potassium channel activity	IEA	GO_REF GO_REF GO_REF
delayed rectifier potassium channel activity	ISS	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

kinesin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTVATGDPVDEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
38			G02815KT	GlyGen
207	N-linked (GlcNAc...) asparagine			UniProt GlyGen
441		30059200 33300544 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database
479		30059200 33300544 40021952 40885482	G49108TO	The O-GlcNAc Database
481			G72747WU	GlyGen
483		30059200 33300544 40021952 40885482	G49108TO	The O-GlcNAc Database