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Guanylyl cyclase C

Summary

UniProt ID: P70106
Gene Symbol: GUCY2C GUC2C
Gene ID: 100135536
Organism: Cavia porcellus (domestic guinea pig)

External Links

Re-Glyco: P70106

Annotation

Keyword: Cell membrane Endoplasmic reticulum GTP-binding Glycoprotein Lyase Receptor Reference proteome Signal Transmembrane helix cGMP biosynthesis

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	Reference
receptor guanylyl cyclase signaling pathway	IEA	GO_REF
intracellular signal transduction	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

receptor guanylyl cyclase signaling pathway

intracellular signal transduction

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

receptor guanylyl cyclase signaling pathway

intracellular signal transduction

Displaying **all 4** entries
GO Term	Evidence Code	Reference
endoplasmic reticulum membrane	ISS	GO_REF
endoplasmic reticulum membrane	IEA	GO_REF
plasma membrane	ISS	GO_REF
plasma membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
peptide receptor activity	IEA	GO_REF
adenylate cyclase activity	IEA	GO_REF
guanylate cyclase activity	ISS	GO_REF
guanylate cyclase activity	IEA	GO_REF GO_REF GO_REF GO_REF
protein kinase activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

cyclase activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

lyase activity [inference]

phosphorus-oxygen lyase activity [inference]

catalytic activity, acting on a protein [inference]

protein kinase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKSPLLGLVVWSLLLQLLQPGLAFWNSQISQNCHNGSYEITVLMMNNYAFQESLESLKTAVNKGLDIVKQRLQEAALYVTVNATFIHSDGLIHKSGDCRSSTCEGLDLLREIARQKRMGCALMGPSCTYSTYQMYLDTELNYPMISAGSFGLSCDHKETLTRMMSPARKLMYFLVDFWKASNLPFKSFSWNTSYVFKNGTESEHCFWYINALEAGVSYFSQVLGFKEMLRGNEELQKILKDPNRRSNVIVMCGTPQTMESLKIDWTATEDTVIILVDLFNNYYLEENATAPDYMKNVLVLTLPPGNSTINTSLSKESLQEFSDFALAYLDGILLFGHMLKTFLRNGENTTAHKFAHAFRNLTFEGSTGPVTLDDSGDIDNTMVLLYTSVDTKKFKPLLFYDTRINQTTPIDTHPTFIWKNHRLPHDIPGLGPHILLIAVCTLAGVVVLILLIALLVLRKYKKDNELRQKKWSHIPPEKILPLETNEANHVSLKIDDDKKRDTVQRLRQCKYDPKRAILKDLKYSDGNFSEKQKIELDKLLPSDFYSLTKFYGTVKLDTRIFGVIEYCERGSLREVLNETISYPDGTIMGWEFKISVLYDIAKGMSYLHSSKIEVHGRLKSTNCVVDSRMVVKITDFGYNSILPPKKDLWTAPEHLRQASTSQKGDVYSFGIIAQEIIMRRETFYTLSCRDQKEKIFRVEHPDGLKPFRPDLFLETAEEKELEVFLLVKNCWEEDPEKRPDFKKIENTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADRLNFMLLPRPVVQSLKEKGIVEPELYEEVTVYFSDIVGFTTICKYSTPMEVVDMLNDLYKSFDQIVDHHDVHKVETIGDAYVVASGLPTRNGNRHAIDISKMALDILSFIGTFELEHLPGLPVWIRIGVHSGPCAAGVVGIKIPRYCLFGDTVNTASRMESTGLPLRIHMSSSTIAILKRVQCQFLYEMRGETYLKGKGTETTYCLTGMKDQEYNLPTPPTVENQQRLQAEFSDMITNSLQKRQATGIKSRKPARVASYKKGTLEYLQLNTTDQDSTYF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	Source
35	N-linked (GlcNAc...) asparagine	UniProt
82	N-linked (GlcNAc...) asparagine	UniProt
191	N-linked (GlcNAc...) asparagine	UniProt
198	N-linked (GlcNAc...) asparagine	UniProt
287	N-linked (GlcNAc...) asparagine	UniProt
306	N-linked (GlcNAc...) asparagine	UniProt
310	N-linked (GlcNAc...) asparagine	UniProt
348	N-linked (GlcNAc...) asparagine	UniProt
405	N-linked (GlcNAc...) asparagine	UniProt