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Prostaglandin E2 receptor EP1 subtype

Summary

UniProt ID: P70597
Gene Symbol: Ptger1
Gene ID: 25637
Organism: Rattus norvegicus (Norway rat)

External Links

PubChem: P70597
Re-Glyco: P70597

Annotation

Keyword: Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Phosphoprotein Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
inflammatory response	IBA	GO_REF
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	GO_REF
adenylate cyclase-activating dopamine receptor signaling pathway	ISO	GO_REF
adenylate cyclase-activating dopamine receptor signaling pathway	IEA	GO_REF
positive regulation of cytosolic calcium ion concentration	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway [inference]

G protein-coupled glutamate receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled glutamate receptor signaling pathway

G protein-coupled dopamine receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled glutamate receptor signaling pathway

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

response to prostaglandin [inference]

response to prostaglandin E

response to chemical [inference]

response to hormone [inference]

response to prostaglandin [inference]

response to prostaglandin E

response to lipid [inference]

response to lipopolysaccharide

response to prostaglandin [inference]

response to prostaglandin E

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to alcohol [inference]

response to prostaglandin E

response to ketone [inference]

response to prostaglandin E

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway [inference]

G protein-coupled glutamate receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled glutamate receptor signaling pathway

G protein-coupled dopamine receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

G protein-coupled glutamate receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled glutamate receptor signaling pathway

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 2** entries
GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	Reference
prostaglandin E receptor activity	IDA	PMID
prostaglandin E receptor activity	IBA	GO_REF
prostaglandin E receptor activity	IEA	GO_REF
D1 dopamine receptor binding	ISO	GO_REF
D1 dopamine receptor binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

dopamine receptor binding [inference]

D1 dopamine receptor binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

prostaglandin receptor activity [inference]

prostaglandin E receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
7	N-linked (GlcNAc...) asparagine	UniProt
24	N-linked (GlcNAc...) asparagine	UniProt
34	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
G alpha (q) signalling events	Rattus norvegicus
Prostanoid ligand receptors	Rattus norvegicus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10808	gastric ulcer	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements