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Lysosomal alpha-glucosidase

Summary

UniProt ID: P70699
Gene Symbol: Gaa
Gene ID: 14387
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003784

GlyConnect

Lysosomal alpha-glucosidase

GlyGen

P70699

PubChem

P70699

The O-GlcNAc Database

P70699

Re-Glyco

P70699

Annotation

Keyword: Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Lysosome Membrane Reference proteome Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	Reference
regulation of the force of heart contraction	IMP	PMID
diaphragm contraction	ISO	GO_REF
diaphragm contraction	IMP	PMID
diaphragm contraction	IEA	GO_REF
heart morphogenesis	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glycophagy

catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glycophagy

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glycophagy

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glycophagy

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glycophagy

glucan catabolic process [inference]

glycogen catabolic process

glycophagy

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glycophagy

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glycophagy

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glycophagy

glucan catabolic process [inference]

glycogen catabolic process

glycophagy

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glycophagy

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy [inference]

glycophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction

skeletal muscle contraction [inference]

involuntary skeletal muscle contraction [inference]

diaphragm contraction

cardiac muscle contraction

respiratory system process [inference]

diaphragm contraction

nervous system process [inference]

neuromuscular process [inference]

behavior [inference]

locomotory behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

heart morphogenesis

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

blood vessel development [inference]

artery development [inference]

aorta development

tissue development

homeostatic process [inference]

cellular homeostasis [inference]

muscle cell cellular homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of the force of heart contraction

regulation of biological quality [inference]

regulation of the force of heart contraction

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GO Term	Evidence Code	Reference
lysosome	ISS	GO_REF
lysosome	ISO	GO_REF
lysosome	TAS	PMID
lysosome	IMP	PMID
lysosome	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

autolysosome lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
alpha-1,4-glucosidase activity	ISS	GO_REF
alpha-1,4-glucosidase activity	ISO	PMID GO_REF GO_REF
alpha-1,4-glucosidase activity	IDA	PMID
alpha-1,4-glucosidase activity	IMP	PMID PMID PMID PMID PMID PMID
alpha-1,4-glucosidase activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

glucosidase activity [inference]

alpha-glucosidase activity

binding [inference]

carbohydrate binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MNIRKPLCSNSVVGACTLISLTTAVILGHLMLRELMLLPQDLHESSSGLWKTYRPHHQEGYKPGPLHIQEQTEQPKEAPTQCDVPPSSRFDCAPDKGISQEQCEARGCCYVPAGQVLKEPQIGQPWCFFPPSYPSYRLENLSSTESGYTATLTRTSPTFFPKDVLTLQLEVLMETDSRLHFKIKDPASKRYEVPLETPRVLSQAPSPLYSVEFSEEPFGVIVRRKLGGRVLLNTTVAPLFFADQFLQLSTSLPSQHITGLGEHLSPLMLSTDWARITLWNRDTPPSQGTNLYGSHPFYLALEDGGLAHGVFLLNSNAMDVILQPSPALTWRSTGGILDVYVFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAIVRQVVENMTRTHFPLDVQWNDLDYMDARRDFTFNQDSFADFPDMVRELHQDGRRYMMIVDPAISSAGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGTTAFPDFTNPETLDWWQDMVSEFHAQVPFDGMWLDMNEPSNFVRGSQQGCPNNELENPPYVPGVVGGILQAATICASSHQFLSTHYNLHNLYGLTEAIASSRALVKTRGTRPFVISRSTFSGHGRYAGHWTGDVRSSWEHLAYSVPDILQFNLLGVPLVGADICGFIGDTSEELCVRWTQLGAFYPFMRNHNDLNSVPQEPYRFSETAQQAMRKAFALRYALLPYLYTLFHRAHVRGDTVARPLFLEFPEDPSTWSVDRQLLWGPALLITPVLEPGKTEVTGYFPKGTWYNMQMVSVDSLGTLPSPSSASSFRSAVQSKGQWLTLEAPLDTINVHLREGYIIPLQGPSLTTTESRKQPMALAVALTASGEADGELFWDDGESLAVLERGAYTLVTFSAKNNTIVNKLVRVTKEGAELQLREVTVLGVATAPTQVLSNGIPVSNFTYSPDNKSLAIPVSLLMGELFQISWS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
140	N-linked (GlcNAc...) asparagine	19349973 30899004	G05724UK G31852PQ G93180LE G39188ZX G25637MV G00406II G66538GV G74724QE G14669DU	GlycoProtDB UniProt GlyGen GlyConnect
142		33300544 40021952 40885482	G49108TO	The O-GlcNAc Database
233	N-linked (GlcNAc...) asparagine			UniProt GlyGen
390	N-linked (GlcNAc...) asparagine	30899004	G83646BJ G06110VR G66538GV G14669DU G63628AV	GlycoProtDB UniProt GlyGen GlyConnect
469		33300544 40021952 40885482	G49108TO	The O-GlcNAc Database
470	N-linked (GlcNAc...) asparagine	19349973 30899004	G05724UK G93180LE G39188ZX G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
883	N-linked (GlcNAc...) asparagine	30899004	G77547TA G93180LE G06110VR G14669DU	UniProt GlyGen GlyConnect
926	N-linked (GlcNAc...) asparagine	30899004	G66537LK G74724QE	UniProt GlyGen GlyConnect
933	N-linked (GlcNAc...) asparagine			UniProt GlyGen