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MIRAGE
Amyloid-beta precursor protein
Summary
- UniProt ID
- P79307
- Gene Symbol
-
- A4
- AD1
- APP
- Gene ID
- 397663
- Organism
- Sus scrofa (pig)
Annotation
- Keyword
-
- Amyloid
- Apoptosis
- Cell adhesion
- Cell membrane
- Cell projection
- Coated pit
- Copper
- Cytoplasm
- Cytoplasmic vesicle
- Disulfide bond
- Endocytosis
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Heparin-binding
- Iron
- Isopeptide bond
- Metal-binding
- Notch signaling pathway
- Nucleus
- Phosphoprotein
- Reference proteome
- Secreted
- Serine protease inhibitor
- Signal
- Sulfation
- Transmembrane helix
- Ubl conjugation
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| nucleus |
| cytoplasm |
| plasma membrane |
| membrane |
| axon |
| early endosome |
| endoplasmic reticulum |
| Golgi apparatus |
| Golgi-associated vesicle |
| GO Term |
|---|
| regulation of synapse structure or activity |
| regulation of translation |
| endocytosis |
| apoptotic process |
Sequence
MLPGLALVLLAAWTARALEVPTDGNAGLLAEPQVAMFCGKLNMHMNVQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRSRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNIDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVADVEEEEAEDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQSLLKTTQEHLPQDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Advanced glycosylation endproduct receptor signaling | Sus scrofa |
| G alpha (q) signalling events | Sus scrofa |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | Sus scrofa |
| Lysosome Vesicle Biogenesis | Sus scrofa |
| Mitochondrial protein degradation | Sus scrofa |
| Platelet degranulation | Sus scrofa |
| Post-translational protein phosphorylation | Sus scrofa |
| Regulation of IGF Activity by IGFBP | Sus scrofa |
| TAK1-dependent IKK and NF-kappa-B activation | Sus scrofa |
| TRAF6 mediated NF-kB activation | Sus scrofa |
