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MAM domain-containing glycosylphosphatidylinositol anchor protein 1

Summary

UniProt ID: P85171
Gene Symbol: Mdga1
Gene ID: 309659
Organism: Rattus norvegicus (Norway rat)

External Links

Re-Glyco: P85171

Annotation

Keyword: Cell membrane Developmental protein Differentiation Disulfide bond GPI-anchor Immunoglobulin domain Neurogenesis Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
neuron migration	ISS	GO_REF
neuron migration	ISO	GO_REF
nervous system development	IBA	GO_REF
brain development	IEP	PMID
spinal cord association neuron differentiation	IEP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

dopamine metabolic process

serotonin metabolic process

indole-containing compound metabolic process [inference]

serotonin metabolic process

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord association neuron differentiation

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

spinal cord association neuron differentiation

cell motility [inference]

cell migration [inference]

neuron migration

forebrain cell migration [inference]

telencephalon cell migration [inference]

cerebral cortex cell migration [inference]

cerebral cortex radially oriented cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly [inference]

inhibitory synapse assembly

presynapse assembly

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly [inference]

inhibitory synapse assembly

synapse organization [inference]

synapse assembly [inference]

inhibitory synapse assembly

presynapse organization [inference]

presynapse assembly

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

brain development

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation [inference]

cell differentiation in spinal cord [inference]

spinal cord association neuron differentiation

neuron differentiation [inference]

central nervous system neuron differentiation [inference]

spinal cord association neuron differentiation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

prepulse inhibition

negative regulation of developmental process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

prepulse inhibition

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

prepulse inhibition

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

regulation of synapse maturation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

regulation of synaptic membrane adhesion

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of synapse maturation

regulation of presynapse organization [inference]

regulation of presynapse assembly

regulation of synaptic membrane adhesion

negative regulation of synapse organization [inference]

negative regulation of synapse assembly

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
Golgi apparatus
plasma membrane	ISO	GO_REF
plasma membrane	IDA	PMID
plasma membrane	IEA	GO_REF
cell surface	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

side of membrane

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MEVTCLLLLALIPFHCRGQGVYAPAQAQIVHAGQACVVKEDNISERVYTIRESDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVSSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKSITFQLTNTTAPPTLKLSVNETLVVNPGENVTVQCLLTGGDPLPQLHWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSLKNATFQITPDMIKESENIQLGQDLKLSCHVDAVPQEKVNYQWFKNGKPARTSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGSPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLALEETPDGKLRVERVSREMSGTYRCQTARYNGFNVRAREAQVQLTVHFPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPVLPAAAAEGPDHAELRLDALTRDSSGNYECSVSNDVGSATCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQLNQHNAMVKAIPVRRVEKGQLLEYTLTDLRVPHSYEIHLTPYTTFGAGDMASRVIHYTEPINSPSLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGTLDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRRQMDPNKVVVMPGSGAPRLSSLQLWGSMTIFLLALQR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
42	N-linked (GlcNAc...) asparagine	UniProt
235	N-linked (GlcNAc...) asparagine	UniProt
257	N-linked (GlcNAc...) asparagine	UniProt
307	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Post-translational modification: synthesis of GPI-anchored proteins	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements