GlyCosmos Portal

Annotation

Keyword: Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Reference proteome Signal-anchor Sodium/potassium transport Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 31 in total

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GO Term	Evidence Code	Reference
potassium ion transport	ISO	GO_REF
potassium ion transport	IEA	GO_REF
sodium ion transport	ISO	GO_REF
sodium ion transport	IEA	GO_REF
intracellular sodium ion homeostasis	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport

potassium ion transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

sodium ion transport

sodium ion transmembrane transport

sodium ion export across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion export across plasma membrane

potassium ion transmembrane transport

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

regulation of potassium ion transport [inference]

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transport [inference]

positive regulation of sodium ion transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

regulation of potassium ion import [inference]

positive regulation of potassium ion import across plasma membrane

regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of sodium ion export across plasma membrane [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport [inference]

positive regulation of potassium ion import across plasma membrane

positive regulation of sodium ion transmembrane transport [inference]

positive regulation of sodium ion export across plasma membrane

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

regulation of membrane potential [inference]

membrane repolarization

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
cytoplasm	IDA	PMID
plasma membrane	ISO	GO_REF
plasma membrane	IEA	GO_REF
sodium:potassium-exchanging ATPase complex	ISO	GO_REF GO_REF
sodium:potassium-exchanging ATPase complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

sodium:potassium-exchanging ATPase complex

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

transporter complex [inference]

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
ATPase activator activity	ISO	GO_REF
ATPase activator activity	IBA	GO_REF
ATPase activator activity	IEA	GO_REF
P-type sodium:potassium-exchanging transporter activity	ISO	GO_REF
protein-macromolecule adaptor activity	ISO	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

ATPase binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

molecular function regulator activity [inference]

molecular function activator activity [inference]

transporter regulator activity [inference]

transporter activator activity

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTKTEKKSFHQSLAEWKLFIYNPSSGEFLGRTSKSWGLILLFYLVFYGFLAALFTFTMWAMLQTLNDEVPKYRDQIPSPGLMVFPKPQTALEYTFSMSEPQTYKKLVEDLESFLKPYSVEEQKNLTSCPDGAPFIQHGPDYRACQFPVSLLEECSGVTDANFGYSKGQPCILVKMNRIIDLIPDGYPQISCLPKEENATIATYPEFGVLDLKYFPYYGKKRHVGYRQPLVAVQVKFDSGLNKKEVTVECHIAGTRNLKNKNERDKFLGRVSFKVTARA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
124	N-linked (GlcNAc...) asparagine	19349973 30899004	G47012YE G51413EV G34029GR G14260UH G55383ZG G06110VR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
197	N-linked (GlcNAc...) asparagine	19349973 19656770 30899004	G97829MZ G39188ZX	GlycoProtDB UniProt GlyGen GlyConnect