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Neurofascin

Summary

UniProt ID: P97685
Gene Symbol: Nfasc
Gene ID: 116690
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: P97685
PubChem: P97685
RaftProt: P97685
Re-Glyco: P97685

Annotation

Keyword: 3D-structure Alternative splicing Cell adhesion Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Phosphoprotein Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
protein localization to paranode region of axon	ISO	GO_REF
axon guidance	ISO	GO_REF
axon guidance	IBA	GO_REF
brain development	IBA	GO_REF
peripheral nervous system development	IEP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

ensheathment of neurons [inference]

axon ensheathment [inference]

myelination

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

paranodal junction assembly

cell junction assembly [inference]

cell-cell junction assembly [inference]

paranodal junction assembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

paranodal junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

paranodal junction assembly

synapse organization

membrane organization [inference]

neuronal ion channel clustering [inference]

clustering of voltage-gated sodium channels

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

transmission of nerve impulse

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

paranodal junction assembly

anatomical structure development [inference]

animal organ development [inference]

brain development

system development [inference]

peripheral nervous system development

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to axon [inference]

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISO	GO_REF
plasma membrane	TAS	Reactome Reactome Reactome Reactome
plasma membrane	IDA	PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

paranodal junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

glial cell projection [inference]

Schwann cell microvillus

actin-based cell projection [inference]

microvillus [inference]

Schwann cell microvillus

axon initial segment

Displaying **all 3** entries
GO Term	Evidence Code	Reference
protein domain specific binding	IPI	PMID
protein binding involved in heterotypic cell-cell adhesion	ISO	GO_REF
cell-cell adhesion mediator activity	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

protein domain specific binding

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

protein binding involved in heterotypic cell-cell adhesion

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MARQQAPPWVHVALILFLLSLGGAIEIPMDPSIQNELTQPPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTSSSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWLVNGDPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCMASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDDNNSPITDYVVQFEEDQFQPGVWHDHSKFPGSVNSAVLHLSPYVNYQFRVIAVNEVGSSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRETWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPETVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGILIGYTLRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSGEAATEESPTPPNEATPTAAPPTLPPTTVGTTGLVSSTDATALAATSEATTVPIIPTVVPTTVATTIATTTTTTAAATTTTTTESPPTTTTGTKIHETAPDEQSIWNVTVLPNSKWANITWKHNFRPGTDFVVEYIDSNHTKKTVPVKAQAQPIQLTDLFPGMTYTLRVYSRDNEGISSTVITFMTSTAYTNNQTDIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVRKDKEETEGNESSEATSPVNAIYSLA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
275				GlyGen
305	N-linked (GlcNAc...) asparagine	34106099	G02815KT	UniProt GlyGen
409	N-linked (GlcNAc...) asparagine			UniProt GlyGen
446	N-linked (GlcNAc...) asparagine			UniProt GlyGen
483	N-linked (GlcNAc...) asparagine			UniProt GlyGen
752	N-linked (GlcNAc...) asparagine	24090084		UniProt GlyGen
778	N-linked (GlcNAc...) asparagine			UniProt GlyGen
866	N-linked (GlcNAc...) asparagine	34106099	G02815KT	UniProt GlyGen
881	N-linked (GlcNAc...) asparagine	34106099	G19379ID G88725PI G25987BV	UniProt GlyGen
918				GlyGen