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Neogenin

Summary

UniProt ID: P97798
Gene Symbol: Neo1 Ngn
Gene ID: 18007
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003825
GlyGen: P97798
PubChem: P97798
The O-GlcNAc Database: P97798
O-GlcNAcAtlas: P97798
Re-Glyco: P97798

Annotation

Keyword: 3D-structure Alternative splicing Cell adhesion Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Phosphoprotein Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
neuron migration	IBA	GO_REF
regulation of transcription, DNA-templated	IDA	PMID
regulation of DNA-templated transcription	IDA	PMID
intracellular iron ion homeostasis	IMP	PMID
axon guidance	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

trans-synaptic signaling, modulating synaptic transmission

cell adhesion [inference]

cell-cell adhesion

cell motility [inference]

cell migration [inference]

neuron migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cell-cell fusion [inference]

syncytium formation by cell-cell fusion [inference]

myoblast fusion

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

multicellular organismal-level iron ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

inorganic ion homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

trans-synaptic signaling, modulating synaptic transmission

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

trans-synaptic signaling, modulating synaptic transmission

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion

negative regulation of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion

negative regulation of secretion by cell [inference]

negative regulation of protein secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of protein secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

negative regulation of secretion by cell [inference]

negative regulation of protein secretion

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of axon regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

negative regulation of response to wounding [inference]

negative regulation of axon regeneration

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of protein secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion

negative regulation of developmental process [inference]

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

negative regulation of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of axon regeneration

regulation of axon regeneration

negative regulation of axon regeneration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of axon regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

negative regulation of response to wounding [inference]

negative regulation of axon regeneration

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration

negative regulation of axon regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

regulation of response to wounding [inference]

regulation of axon regeneration

negative regulation of axon regeneration

negative regulation of response to wounding [inference]

negative regulation of axon regeneration

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration

negative regulation of axon regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

trans-synaptic signaling, modulating synaptic transmission

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of BMP signaling pathway

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

negative regulation of secretion by cell [inference]

negative regulation of protein secretion

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration

negative regulation of axon regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration

negative regulation of axon regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion

negative regulation of secretion by cell [inference]

negative regulation of protein secretion

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	Reference
nucleoplasm	ISO	GO_REF
Golgi apparatus	ISO	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	TAS	Reactome Reactome Reactome
plasma membrane	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

site of polarized growth [inference]

growth cone

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

cell body [inference]

neuronal cell body

Displaying **all 4** entries
GO Term	Evidence Code	Reference
signaling receptor activity	IPI	PMID PMID
co-receptor binding	ISO	GO_REF
cadherin binding	IDA	PMID
BMP receptor binding	IPI	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor serine/threonine kinase binding [inference]

transmembrane receptor protein serine/threonine kinase binding [inference]

BMP receptor binding

co-receptor binding

cell adhesion molecule binding [inference]

cadherin binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAAEREAGRLLCTSSSRRCCPPPPLLLLLPLLLLLGRPASGAAATKSGSPPQSAGASVRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWEQNRQPLLLDDRIVKLPSGTLVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVARERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNGEIQNYKLYYMEKGTDKEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMPNDQALGSAGKGSRLPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVVIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPSSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDPEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPLYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
84	N-linked (GlcNAc...) asparagine			UniProt GlyGen
221	N-linked (GlcNAc...) asparagine	19349973 19656770	G80920RR	GlycoProtDB UniProt GlyGen
337	N-linked (GlcNAc...) asparagine			UniProt GlyGen
501	N-linked (GlcNAc...) asparagine	19349973 19656770 30899004	G20528HD G74724QE	GlycoProtDB UniProt GlyGen
520	N-linked (GlcNAc...) asparagine	30899004	G02815KT G06110VR	GlycoProtDB UniProt GlyGen
670	N-linked (GlcNAc...) asparagine	19349973	G50282JC	UniProt GlyGen
746	N-linked (GlcNAc...) asparagine			UniProt GlyGen
883				GlyGen
940	N-linked (GlcNAc...) asparagine		G39446WN	UniProt GlyGen
1177			G18647XP	GlyGen