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E-selectin

Summary

UniProt ID: P98110
Gene Symbol: SELE
Gene ID: 397508
Organism: Sus scrofa (pig)

External Links

PubChem: P98110
Re-Glyco: P98110

Annotation

Keyword: Calcium Cell adhesion Cell membrane Disulfide bond EGF-like domain Glycoprotein Lectin Metal-binding Reference proteome Repeat Signal Sushi Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
heterophilic cell-cell adhesion	IBA	GO_REF
response to cytokine	IBA	GO_REF
leukocyte tethering or rolling	IBA	GO_REF
positive regulation of leukocyte tethering or rolling	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

heterophilic cell-cell adhesion

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

response to stimulus [inference]

response to chemical [inference]

response to peptide [inference]

response to cytokine

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

Displaying **all 2** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
external side of plasma membrane	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	Reference
sialic acid binding	IBA	GO_REF
metal ion binding
oligosaccharide binding	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

carbohydrate binding [inference]

oligosaccharide binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

sialic acid binding

cation binding [inference]

metal ion binding

organic acid binding [inference]

carboxylic acid binding [inference]

sialic acid binding

carbohydrate derivative binding [inference]

sialic acid binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MIASQFLSALPLVLLLLRESGAWSYSASTETMTFDDASAYCQQRYTHLVAIQNHAEIEYLNSTFNYSASYYWIGIRKINGTWTWIGTKKALTPEATNWAPGEPNNKQSNEDCVEIYIKRDKDSGKWNDERCSKKKLALCYTAACTPTSCSGHGECIETINSSTCQCYPGFRGLQCEQVVECDALENPVNGVVTCPQSLPWNTTCAFECKEGFELIGPEHLQCTSSGSWDGKKPTCKAVTCDTVGHPQNGDVSCNHSSIGEFAYKSTCHFTCAEGFGLQGPAQIECTAQGQWTQQAPVCKAVKCPAVSQPKNGLVKFTHSPTGEFTYKSSCAFSCEEGFELRGSAQLACTSQGQWTQEVPSCQVVQCSSLEVPREINMSCSGEPVFGAVCTFACPEGWMLNGSVALTCGATGHWSGMLPTCEAPAESKIPLAMGLAAGGVSFMTSASFLLWLLKRLRKRAKKFVPSSSSECLQPNGSYQMPSDLI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
61	N-linked (GlcNAc...) asparagine	UniProt
65	N-linked (GlcNAc...) asparagine	UniProt
79	N-linked (GlcNAc...) asparagine	UniProt
160	N-linked (GlcNAc...) asparagine	UniProt
201	N-linked (GlcNAc...) asparagine	UniProt
254	N-linked (GlcNAc...) asparagine	UniProt
376	N-linked (GlcNAc...) asparagine	UniProt
400	N-linked (GlcNAc...) asparagine	UniProt