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MIRAGE
Intercellular adhesion molecule 1
Summary
- UniProt ID
- Q00238
- Gene Symbol
- Icam1
- Gene ID
- 25464
- Organism
- Rattus norvegicus (Norway rat)
External Links
- Re-Glyco
- Q00238
Annotation
- Keyword
- Cell adhesion Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Reference proteome Repeat Signal Transmembrane helix Ubl conjugation
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| ovarian follicle development | ||
| response to hypoxia | ||
| response to amphetamine | ||
| T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | ||
| acute inflammatory response to antigenic stimulus |
GO Hierarchy
biological process
immune system process [inference]
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| immunological synapse | ||
| obsolete extracellular space |
|
|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| integrin binding | ||
| integrin binding | ||
| integrin binding | ||
| integrin binding | ||
| protein-containing complex binding |
Sequence
MASTRARPMLPLLLVLVAVVIPGPVGAQVSIHPTEAFLPRGGSVQVNCSSSCEDENLGLGLETNWMKDELSSGHNWKLFKLSDIGEDSRPLCFENCGTTQSSASATITVYSFPERVELDPLPAWQQVGKNLILRCLVEGGAPRTQLSVVLLRGNETLSRQAVDGDPKEITFTVLASRGDHGANFSCFTELDLRPQGLSLFKNVSEVRQLRTFDLPTRVLKLDTPDLLEVGTQQKFLCSLEGLFPASEAQIYLEMGGQMLTLESTNSRDFVSATASVEVTEKLDRTLQLRCVLELADQTLEMEKTLRIYNFSAPILTLSQPEVSEGDQVTVKCEAHGGAQVVLLNSTSPRPPTSQGTSPRPPTSQIQFTLNASPEDHKRRFFCSAALEVDGKSLFKNQTLELHVLYGPHLDKKDCLGNWTWQEGSQQTLTCQPQGNPAPNLTCSRKADGVPLPIGMVKSVKREMNGTYKCRAFSSRGSITRDVHLTVLYHDQNTWVIIVGVLVLIIAGFVIVASIYTYYRQRKIRIYKLQKAQEEALKLKVQAPPP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 47 |
|
|
||
| 154 |
|
|
||
| 183 |
|
|
||
| 202 |
|
|
||
| 309 |
|
|
||
| 344 |
|
|
||
| 396 |
|
|
||
| 417 |
|
|
||
| 439 |
|
|
||
| 464 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Rattus norvegicus |
| Integrin cell surface interactions | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13141 | uveitis | |
| DOID:11713 | diabetic angiopathy | |
| DOID:13252 | mesenteric vascular occlusion | |
| DOID:10952 | nephritis | |
| DOID:10591 | pre-eclampsia |
