T-lymphocyte activation antigen CD80
| GO Term | Evidence Code | Reference |
|---|---|---|
| negative regulation of T cell mediated immunity | ||
| immune response | ||
| cell surface receptor signaling pathway | ||
| T cell costimulation | ||
| T cell costimulation |
| GO Term | Evidence Code | Reference |
|---|---|---|
| external side of plasma membrane | ||
| external side of plasma membrane | ||
| cell surface | ||
| protein complex involved in cell adhesion |
| GO Term | Evidence Code | Reference |
|---|---|---|
| coreceptor activity | ||
| receptor ligand activity | ||
| receptor ligand activity |
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 93 |
|
|
||
| 99 |
|
|
||
| 149 |
|
|
||
| 189 |
|
|
||
| 210 |
|
|
||
| 214 |
|
|
| Pathway Name | Organism |
|---|---|
| CD28 co-stimulation | Mus musculus |
| CD28 dependent PI3K/Akt signaling | Mus musculus |
| CD28 dependent Vav1 pathway | Mus musculus |
| Co-inhibition by CTLA4 | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: April 6, 2026