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MIRAGE
Vascular endothelial growth factor A, long form
Summary
- UniProt ID
- Q00731
- Gene Symbol
-
- Vegf
- Vegfa
- Gene ID
- 22339
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative initiation
- Alternative promoter usage
- Alternative splicing
- Angiogenesis
- Cell membrane
- Cytoplasm
- Developmental protein
- Differentiation
- Disulfide bond
- Endoplasmic reticulum
- Extracellular matrix
- Glycoprotein
- Golgi apparatus
- Growth factor
- Heparin-binding
- Mitogen
- Nucleus
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum |
| Golgi apparatus |
| adherens junction |
| cell surface |
| VEGF-A complex |
| extracellular region |
| extracellular space |
| nucleus |
| cytoplasm |
| plasma membrane |
Sequence
MTDRQTDTAPSPSAHLLAGGLPTVDAAASREEPKPAPGGGVEGVGARGIARKLFVQLLGSSRSVVAVVCAAGDKPIGAGRSASSGLEKPGPEKRGEEEKEEERGPQWALGSQEPSSWTGEAAVCADSAPAARAPQAPARASVPEGRGARQGAQESGLPRSPSRRGSASRAGPGRASETMNFLLSWVHWTLALLLYLHHAKWSQAAPTTEGEQKSHEVIKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNITMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPEKKSVRGKGKGQKRKRKKSRFKSWSVHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 278 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Platelet degranulation | Mus musculus |
| VEGF binds to VEGFR leading to receptor dimerization | Mus musculus |
| VEGF ligand-receptor interactions | Mus musculus |
| VEGFA-VEGFR2 Pathway | Mus musculus |
| VEGFR2 mediated cell proliferation | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060193 | amyotrophic lateral sclerosis type 1 | |
| DOID:11198 | DiGeorge syndrome | |
| DOID:12716 | newborn respiratory distress syndrome | |
| DOID:8893 | psoriasis |
