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Transcription factor E2F1
Summary
- UniProt ID
- Q01094
- Gene Symbol
-
- E2F1
- RBBP3
- Gene ID
- 1869
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Apoptosis
- Cell cycle
- DNA-binding
- Host-virus interaction
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| RNA polymerase II transcription regulator complex |
| centrosome |
| Rb-E2F complex |
| chromatin |
| nucleus |
| cytoplasm |
| protein-containing complex |
| nucleoplasm |
Sequence
MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFDCDFGDLTPLDF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 49 |
|
|
||
| 75 |
|
|
||
| 382 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of NOXA and translocation to mitochondria | Homo sapiens |
| Activation of PUMA and translocation to mitochondria | Homo sapiens |
| Cyclin A:Cdk2-associated events at S phase entry | Homo sapiens |
| Cyclin D associated events in G1 | Homo sapiens |
| Cyclin E associated events during G1/S transition | Homo sapiens |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | Homo sapiens |
| G1/S-Specific Transcription | Homo sapiens |
| G2 Phase | Homo sapiens |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | Homo sapiens |
| Oncogene Induced Senescence | Homo sapiens |
