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Epidermal growth factor receptor

Summary

UniProt ID

Q01279

Gene Symbol

Egfr

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003854

GlyConnect

2297

GlyGen

Q01279

PubChem

Q01279

Annotation

Keyword

ATP-binding
Cell membrane
Developmental protein
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Hydroxylation
Isopeptide bond
Methylation
Nucleus
Palmitate
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **11 - 20** of 80 in total

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GO Term
cell population proliferation
positive regulation of cell population proliferation
epidermis development
phosphorylation
positive regulation of cell migration
regulation of cell population proliferation
negative regulation of protein catabolic process
astrocyte activation
digestive tract morphogenesis
neuron projection morphogenesis

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GO Term
basolateral plasma membrane
apical plasma membrane
early endosome membrane
membrane raft
endosome
endoplasmic reticulum membrane
basal plasma membrane
cell surface
ruffle membrane
perinuclear region of cytoplasm

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GO Term
chromatin binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
transmembrane signaling receptor activity
signaling receptor binding
kinase activity
protein-containing complex binding
protein kinase binding
transmembrane receptor protein tyrosine kinase activator activity
ubiquitin protein ligase binding

Annotation information from UniProt.

Sequence

MRPSGTARTTLLVLLTALCAAGGALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMYNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALAILSNYGTNRTGLRELPMRNLQEILIGAVRFSNNPILCNMDTIQWRDIVQNVFMSNMSMDLQSHPSSCPKCDPSCPNGSCWGGGEENCQKLTKIICAQQCSHRCRGRSPSDCCHNQCAAGCTGPRESDCLVCQKFQDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGPDYYEVEEDGIRKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFKYCTAISGDLHILPVAFKGDSFTRTPPLDPRELEILKTVKEITGFLLIQAWPDNWTDLHAFENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKLFGTPNQKTKIMNNRAEKDCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRECVEKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGIMGENNTLVWKYADANNVCHLCHANCTYGCAGPGLQGCEVWPSGPKIPSIATGIVGGLLFIVVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQQGFFNSPSTSRTPLLSSLSATSNNSTVACINRNGSCRVKEDAFLQRYSSDPTGAVTEDNIDDAFLPVPEYVNQSVPKRPAGSVQNPVYHNQPLHPAPGRDLHYQNPHSNAVGNPEYLNTAQPTCLSSGFNSPALWIQKGSHQMSLDNPDYQQDFFPKETKPNGIFKGPTAENAEYLRVAPPSSEFIGA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
128	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
175	N-linked (GlcNAc...) asparagine	17330941	G90659AW	GlycoProtDB UniProt GlyGen
196	N-linked (GlcNAc...) asparagine		G02815KT	GlycoProtDB UniProt GlyGen
234				GlycoProtDB
352	N-linked (GlcNAc...) asparagine	16944957	G80920RR G39188ZX	GlycoProtDB UniProt GlyGen GlyConnect
413	N-linked (GlcNAc...) asparagine			UniProt GlyGen
444	N-linked (GlcNAc...) asparagine	16944957	G24193ZC	GlycoProtDB UniProt GlyGen
528	N-linked (GlcNAc...) asparagine		G43223CG	GlycoProtDB UniProt GlyGen
568	N-linked (GlcNAc...) asparagine		G27947YN	GlycoProtDB UniProt GlyGen
603	N-linked (GlcNAc...) asparagine		G27947YN	GlycoProtDB UniProt GlyGen