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Beta-2-glycoprotein 1

Summary

UniProt ID: Q01339
Gene Symbol: Apoh B2gp1
Gene ID: 11818
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003855

GlyConnect

Beta-2-glycoprotein 1

GlyGen

Q01339

The Human Metabolome Database

HMDBP12361

RaftProt

Q01339

Re-Glyco

Q01339

Annotation

Keyword: Disulfide bond Glycoprotein Heparin-binding Reference proteome Repeat Secreted Signal Sushi

Gene Ontology (GO)

Displaying entries **1 - 5** of 32 in total

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GO Term	Evidence Code	Reference
negative regulation of endothelial cell proliferation	ISO	GO_REF
negative regulation of endothelial cell proliferation	IEA	GO_REF
blood coagulation, intrinsic pathway	ISO	GO_REF
blood coagulation, intrinsic pathway	IEA	GO_REF
negative regulation of endothelial cell migration	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein activation cascade [inference]

blood coagulation, intrinsic pathway

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein activation cascade [inference]

blood coagulation, intrinsic pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration

animal gross anatomical part developmental process [inference]

animal organ development [inference]

animal organ regeneration

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

acylglycerol transport [inference]

triglyceride transport

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process

positive regulation of triglyceride catabolic process

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

negative regulation of fibrinolysis

positive regulation of response to wounding [inference]

positive regulation of wound healing [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

positive regulation of multicellular organismal process [inference]

positive regulation of coagulation [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

positive regulation of hemostasis [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

negative regulation of metabolic process [inference]

negative regulation of respiratory burst

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

negative regulation of myeloid cell apoptotic process

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of coagulation [inference]

negative regulation of blood coagulation

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of fibrinolysis

negative regulation of hemostasis [inference]

negative regulation of blood coagulation

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of blood coagulation

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

negative regulation of blood coagulation

regulation of fibrinolysis

negative regulation of fibrinolysis

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

positive regulation of response to external stimulus [inference]

negative regulation of fibrinolysis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

negative regulation of fibrinolysis

positive regulation of response to wounding [inference]

positive regulation of wound healing [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

regulation of response to stress [inference]

regulation of response to wounding [inference]

regulation of wound healing [inference]

regulation of blood coagulation

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

negative regulation of blood coagulation

regulation of fibrinolysis

negative regulation of fibrinolysis

negative regulation of wound healing [inference]

negative regulation of blood coagulation

positive regulation of wound healing [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

negative regulation of response to wounding [inference]

negative regulation of wound healing [inference]

negative regulation of blood coagulation

positive regulation of response to wounding [inference]

positive regulation of wound healing [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of cellular process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of respiratory burst

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process

positive regulation of triglyceride catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of lipid catabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of respiratory burst [inference]

negative regulation of respiratory burst

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process

positive regulation of triglyceride catabolic process

regulation of lipid catabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of triglyceride metabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process

positive regulation of triglyceride catabolic process

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

regulation of muscle cell apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

regulation of smooth muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

regulation of myeloid cell apoptotic process [inference]

negative regulation of myeloid cell apoptotic process

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

negative regulation of myeloid cell apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

negative regulation of myeloid cell apoptotic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process

positive regulation of triglyceride catabolic process

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of endothelial cell proliferation

negative regulation of metabolic process [inference]

negative regulation of respiratory burst

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process

negative regulation of myeloid cell apoptotic process

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration

regulation of multicellular organismal process [inference]

regulation of coagulation [inference]

regulation of blood coagulation

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

negative regulation of blood coagulation

regulation of fibrinolysis

negative regulation of fibrinolysis

negative regulation of coagulation [inference]

negative regulation of blood coagulation

positive regulation of coagulation [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

positive regulation of multicellular organismal process [inference]

positive regulation of coagulation [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

negative regulation of multicellular organismal process [inference]

negative regulation of coagulation [inference]

negative regulation of blood coagulation

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of hemostasis [inference]

regulation of blood coagulation

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

negative regulation of blood coagulation

regulation of fibrinolysis

negative regulation of fibrinolysis

negative regulation of hemostasis [inference]

negative regulation of blood coagulation

positive regulation of hemostasis [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

regulation of biological quality [inference]

regulation of body fluid levels [inference]

regulation of hemostasis [inference]

regulation of blood coagulation

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

negative regulation of blood coagulation

regulation of fibrinolysis

negative regulation of fibrinolysis

negative regulation of hemostasis [inference]

negative regulation of blood coagulation

positive regulation of hemostasis [inference]

positive regulation of blood coagulation [inference]

negative regulation of fibrinolysis

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GO Term	Evidence Code	Reference
obsolete extracellular space
cell surface	ISO	GO_REF GO_REF
cell surface	IEA	GO_REF
very-low-density lipoprotein particle	ISO	GO_REF
very-low-density lipoprotein particle	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex [inference]

lipoprotein particle [inference]

plasma lipoprotein particle [inference]

high-density lipoprotein particle

triglyceride-rich plasma lipoprotein particle [inference]

very-low-density lipoprotein particle

chylomicron

extracellular protein-containing complex [inference]

plasma lipoprotein particle [inference]

high-density lipoprotein particle

triglyceride-rich plasma lipoprotein particle [inference]

very-low-density lipoprotein particle

chylomicron

cellular anatomical structure [inference]

cell surface

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
phospholipid binding	ISO	GO_REF
phospholipid binding	IEA	GO_REF
heparin binding
lipid binding	ISO	GO_REF GO_REF
lipid binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

lipase binding

identical protein binding

lipid binding

phospholipid binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

lipase activator activity [inference]

lipoprotein lipase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

lipase activator activity [inference]

lipoprotein lipase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MVSPVLALFSAFLCHVAIAGRICPKPDDLPFATVVPLKTSYDPGEQIVYSCKPGYVSRGGMRRFTCPLTGMWPINTLRCVPRVCPFAGILENGIVRYTSFEYPKNISFACNPGFFLNGTSSSKCTEEGKWSPDIPACARITCPPPPVPKFALLKDYRPSAGNNSLYQDTVVFKCLPHFAMIGNDTVMCTEQGNWTRLPECLEVKCPFPPRPENGYVNYPAKPVLLYKDKATFGCHETYKLDGPEEAECTKTGTWSFLPTCRESCKLPVKKATVLYQGMRVKIQEQFKNGMMHGDKIHFYCKNKEKKCSYTVEAHCRDGTIEIPSCFKEHSSLAFWKTDASELTPC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
33	O-linked (GalNAc...) threonine			UniProt GlyGen
105	N-linked (GlcNAc...) asparagine	17330941	G88989HA	GlycoProtDB UniProt GlyGen
117	N-linked (GlcNAc...) asparagine	16944957 17330941	G57489SP	GlycoProtDB UniProt GlyGen
162	N-linked (GlcNAc...) asparagine	16944957 17330941 20571061	G15488CF G39397SW G60033FS	GlycoProtDB UniProt GlyGen GlyConnect
183	N-linked (GlcNAc...) asparagine	17330941		GlycoProtDB UniProt GlyGen
193	N-linked (GlcNAc...) asparagine	17330941		GlycoProtDB UniProt GlyGen