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MIRAGE
Sodium/calcium exchanger 1
Summary
- UniProt ID
- Q01728
- Gene Symbol
-
- Ncx1
- Slc8a1
- Gene ID
- 29715
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative splicing
- Antiport
- Calcium transport
- Calmodulin-binding
- Cell membrane
- Cell projection
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Sodium transport
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| basolateral plasma membrane |
| Z disc |
| T-tubule |
| sarcolemma |
| microtubule |
| postsynaptic density |
| intercalated disc |
| dendritic spine |
| dendritic shaft |
| axon terminus |
| GO Term |
|---|
| calcium ion binding |
| calmodulin binding |
| cytoskeletal protein binding |
| ankyrin binding |
| transmembrane transporter binding |
| calcium:sodium antiporter activity |
Sequence
MLRLSLPPNVSMGFRLVTLVALLFTHVDHITADTEAETGGNETTECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMDVVENDPVSKVFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSEVSEDGILDSNHVSAIACLGSPNTATITIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFIEIGEPRLVEMSEKKALLLNELGGFTLTEGKKMYGQPVFRKVHARDHPIPSTVISISEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSSLEAYCHIKGF
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ion homeostasis | Rattus norvegicus |
| Reduction of cytosolic Ca++ levels | Rattus norvegicus |
| Sodium/Calcium exchangers | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2316 | brain ischemia |
