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Catenin beta-1
Summary
- UniProt ID
- Q02248
- Gene Symbol
-
- Catnb
- Ctnnb1
- Gene ID
- 12387
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Cell adhesion
- Cell junction
- Cell membrane
- Cell projection
- Cytoskeleton
- Glycoprotein
- Neurogenesis
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- S-nitrosylation
- Synapse
- Transcription regulation
- Ubl conjugation
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| apical part of cell |
| perinuclear region of cytoplasm |
| spindle pole |
| transcription regulator complex |
| centrosome |
| fascia adherens |
| bicellular tight junction |
| intercalated disc |
| lateral plasma membrane |
| catenin complex |
Sequence
MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEALGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL
Glycosylation Sites
G49108TO
G36379GD
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Adherens junctions interactions | Mus musculus |
| Apoptotic cleavage of cell adhesion proteins | Mus musculus |
| Beta-catenin phosphorylation cascade | Mus musculus |
| Ca2+ pathway | Mus musculus |
| Deactivation of the beta-catenin transactivating complex | Mus musculus |
| Degradation of beta-catenin by the destruction complex | Mus musculus |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | Mus musculus |
| Formation of the beta-catenin:TCF transactivating complex | Mus musculus |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | Mus musculus |
| Myogenesis | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050535 | exudative vitreoretinopathy | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:10283 | prostate cancer | |
| DOID:11054 | urinary bladder cancer | |
| DOID:2394 | ovarian cancer | |
| DOID:2999 | granulosa cell tumor |
