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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor 4
Summary
- UniProt ID
- Q03142
- Gene Symbol
-
- Fgfr4
- Fgfr-4
- Mpk-11
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003870
- GlyGen
- Q03142
- PubChem
- Q03142
- RaftProt
- Q03142
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Cell membrane
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| organ induction |
| fibroblast growth factor receptor signaling pathway |
| positive regulation of ERK1 and ERK2 cascade |
| negative regulation of fibroblast growth factor production |
| GO Term |
|---|
| plasma membrane |
| receptor complex |
| endosome |
| endoplasmic reticulum |
| GO Term |
|---|
| heparin binding |
| fibroblast growth factor receptor activity |
| fibroblast growth factor binding |
| ATP binding |
Sequence
MWLLLALLSIFQGTPALSLEASEEMEQEPCLAPILEQQEQVLTVALGQPVRLCCGRTERGRHWYKEGSRLASAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMTVVHNLTLLMDDSLTSISNDEDPKTLSSSSSGHVYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPMPTIHWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENSLGSIRYSYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHVVINGSSFGADGFPYVQVLKTTDINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDLTWTTATPEARYTDIILYVSGSLVLLVLLLLAGVYHRQVIRGHYSRQPVTIQKLSRFPLARQFSLESRSSGKSSLSLVRGVRLSSSGPPLLTGLVNLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPSRPDQTSTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPFSPSNGDASSTCSSSDSVFSHDPLPLEPSPFPFSDSQTT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 109 | N-linked (GlcNAc...) asparagine |
|
||
| 255 | N-linked (GlcNAc...) asparagine | |||
| 287 | N-linked (GlcNAc...) asparagine |
|
||
| 308 | N-linked (GlcNAc...) asparagine |
|
||
| 319 | N-linked (GlcNAc...) asparagine |
|
G77547TA
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR4 ligand binding and activation | Mus musculus |
| FRS-mediated FGFR4 signaling | Mus musculus |
| Negative regulation of FGFR4 signaling | Mus musculus |
| PI-3K cascade:FGFR4 | Mus musculus |
| PI3K Cascade | Mus musculus |
| PI3K/AKT Signaling | Mus musculus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Mus musculus |
| Phospholipase C-mediated cascade; FGFR4 | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
| SHC-mediated cascade:FGFR4 | Mus musculus |
