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Tenascin-R

Summary

UniProt ID: Q05546
Gene Symbol: Tnr
Gene ID: 25567
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: Q05546
PubChem: Q05546
RaftProt: Q05546
Re-Glyco: Q05546

Annotation

Keyword: 3D-structure Alternative splicing Cell adhesion Coiled coil Disulfide bond EGF-like domain Extracellular matrix Phosphoprotein Proteoglycan Reference proteome Repeat Sialic acid Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	Reference
neuron cell-cell adhesion	ISO	GO_REF
negative regulation of cell adhesion	IDA	PMID
negative regulation of cell adhesion	IEA	GO_REF
nervous system development	TAS	PMID
nervous system development	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

neuron cell-cell adhesion

cell motility [inference]

cell migration [inference]

forebrain cell migration [inference]

telencephalon cell migration

neuroblast migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning

neuromuscular process [inference]

neuromuscular process controlling balance

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning

locomotory behavior [inference]

locomotory exploration behavior

exploration behavior [inference]

locomotory exploration behavior

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

negative regulation of synaptic transmission

positive regulation of synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of developmental growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of transmission of nerve impulse

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of transmission of nerve impulse

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to wounding [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to wounding [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of response to wounding [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to wounding [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axonogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of cell differentiation

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of developmental growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of transmission of nerve impulse

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

regulation of transmission of nerve impulse [inference]

positive regulation of transmission of nerve impulse

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

negative regulation of synaptic transmission

positive regulation of synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

regulation of cell adhesion

negative regulation of cell adhesion

negative regulation of cell-cell adhesion

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion

regulation of cell differentiation

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of transmission of nerve impulse

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axonogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of cell motility [inference]

regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

positive regulation of nervous system process [inference]

positive regulation of transmission of nerve impulse

regulation of transmission of nerve impulse [inference]

positive regulation of transmission of nerve impulse

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of transmission of nerve impulse

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
obsolete extracellular space
cell surface	ISO	GO_REF
extracellular matrix	ISO	GO_REF
extracellular matrix	IBA	GO_REF
membrane raft	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

protein complex involved in cell adhesion [inference]

protein complex involved in cell-matrix adhesion [inference]

tenascin complex

extracellular protein-containing complex [inference]

tenascin complex

cellular anatomical structure [inference]

cell surface

membrane [inference]

membrane microdomain [inference]

membrane raft

cell junction [inference]

synapse [inference]

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

external encapsulating structure [inference]

extracellular matrix

specialized extracellular matrix [inference]

synapse-associated extracellular matrix [inference]

perisynaptic extracellular matrix

perineuronal net

Displaying 1 entry
GO Term	Evidence Code	Reference
integrin binding	IPI	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGIEGETVVLKNMLIGVNLILLGSMLKPSECRLEVTTERVQRQTVEEEGGASSYNTSSKEQPMVFNHVYNINVPLESLCSSGLEASAEQDVSAEDDTLAEYTGQTSDHESQVTFTHKINLPKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNTNCCQESAATGQLDYVPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGQCANGTCLCQEGYAGEDCSQRRCLNACSGRGHCQEGLCICEEGYQGPDCSAVTPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPSLGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFTPKNNEGGVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKEQARGPPTSASVSTVIDGPTQILVRDVSDTVAFVEWTPPRAKVDFILLKYGLVGGEGGKTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESDASSTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTLTDLVPGTEYGVGISAVMNSKQSIPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVLLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKNITISNVTKDSLTVSWSPPVAPFDYYEYPIDHPSGRLDSSVVPNTVTEFTITRLYPASQYEISLNSVRGREESERICTLVHTAMDSPMDLIATNITPTEALLQWKAPMGEVENYVIVLTHFAMAGETILVDGVSEEFQLVDLLPRTHYTVTMYATSGPLVSGTIATNFSTLLDPPANLTASEVTRQSALISWQPPRAAIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLSENTDYTVLLQAAQEATRSSLTSTIFTTGGRVFSHPQDCAQHLMNGDTLSGVYTIFLNGELSHKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNYHRITAQGRYELRVDMRDGQEAVFAYYDKFAVEDSRSLYKLRIGGYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMRPYIHRLTAGRKRRALKF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 18 in total

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Position	Description	Source
55	N-linked (GlcNAc...) asparagine	UniProt GlyGen
176	O-linked (Xyl...) (chondroitin sulfate) serine	UniProt GlyGen
180	N-linked (GlcNAc...) asparagine	UniProt GlyGen
198	N-linked (GlcNAc...) asparagine	UniProt GlyGen
271	O-linked (Xyl...) (chondroitin sulfate) serine	UniProt GlyGen
278	N-linked (GlcNAc...) asparagine	UniProt GlyGen
302	O-linked (Xyl...) (chondroitin sulfate) serine	UniProt GlyGen
327		GlyGen
391	N-linked (GlcNAc...) asparagine	UniProt GlyGen
469	N-linked (GlcNAc...) asparagine	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
ECM proteoglycans	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

International Collaboration

Acknowledgements