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MIRAGE

Sodium-dependent phosphate transport protein 2A

Summary

UniProt ID

Q06496

Gene Symbol

Slc17a2
Slc34a1

Gene ID

[25548]

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q06496
Re-Glyco: Q06496

Annotation

Keyword: Cell membrane Disulfide bond Glycoprotein Phosphoprotein Reference proteome Sodium transport Symport Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 47 in total

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GO Term	Evidence Code	Reference
ossification	IEP	PMID
kidney development	IEP	PMID
phosphate ion transport	ISO	GO_REF
phosphate ion transport	IEA	GO_REF
response to nutrient	IEP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

cellular response to metal ion

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

phosphate ion transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

arsenate ion transmembrane transport

multicellular organismal process [inference]

ossification

tissue remodeling [inference]

bone remodeling

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

odontogenesis [inference]

odontogenesis of dentin-containing tooth [inference]

dentinogenesis

anatomical structure formation involved in morphogenesis [inference]

dentinogenesis

anatomical structure development [inference]

animal organ development [inference]

kidney development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular phosphate ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular phosphate ion homeostasis

inorganic ion homeostasis [inference]

phosphate ion homeostasis

intracellular phosphate ion homeostasis

calcium ion homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

response to peptide hormone

response to growth hormone

response to parathyroid hormone

cellular response to parathyroid hormone stimulus

response to thyroid hormone

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

response to nutrient levels [inference]

response to nutrient

response to vitamin [inference]

response to vitamin A

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

response to chemical [inference]

response to nutrient

response to vitamin [inference]

response to vitamin A

response to xenobiotic stimulus

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

response to peptide hormone

response to growth hormone

response to parathyroid hormone

cellular response to parathyroid hormone stimulus

response to thyroid hormone

response to metal ion [inference]

response to lipid [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

cellular response to metal ion

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

response to peptide

response to nitrogen compound [inference]

response to alkaloid [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

response to staurosporine [inference]

cellular response to staurosporine

response to peptide hormone

response to growth hormone

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

response to oxygen-containing compound [inference]

response to estradiol

response to peptide hormone

response to growth hormone

response to salt [inference]

response to sodium phosphate

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to phosphate starvation

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to parathyroid hormone stimulus

cellular response to metal ion

cellular response to nitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to staurosporine

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

inorganic anion transport [inference]

phosphate ion transport

inorganic diphosphate transport

arsenite transport [inference]

arsenate ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

phosphate ion transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

arsenate ion transmembrane transport

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of phosphate transport [inference]

regulation of sodium-dependent phosphate transport [inference]

positive regulation of sodium-dependent phosphate transport

regulation of phosphate transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of phosphate transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of sodium-dependent phosphate transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of sodium-dependent phosphate transport

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of phosphate transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of phosphate transmembrane transport

regulation of biological quality [inference]

regulation of membrane potential [inference]

positive regulation of membrane potential

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	Reference
nucleoplasm
endosome	IDA	PMID
cytosol
plasma membrane	ISO	GO_REF
plasma membrane	EXP	PMID PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

membraneless organelle [inference]

intracellular membraneless organelle [inference]

spindle [inference]

mitotic spindle

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membraneless organelle [inference]

spindle [inference]

mitotic spindle

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

perinuclear region of cytoplasm

cluster of actin-based cell projections [inference]

brush border

supramolecular complex [inference]

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
sodium:phosphate symporter activity	ISS	GO_REF
sodium:phosphate symporter activity	ISO	GO_REF
sodium:phosphate symporter activity	IDA	PMID PMID PMID PMID
sodium:phosphate symporter activity	IMP	PMID
sodium:phosphate symporter activity	IBA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

phosphate transmembrane transporter activity [inference]

sodium:phosphate symporter activity

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

sodium:phosphate symporter activity

binding [inference]

protein binding [inference]

protein domain specific binding [inference]

PDZ domain binding

identical protein binding

protein-containing complex binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MMSYSERLGGPAVSPLPVRGRHMVHGAAFAYVPSPQVLHRIPGTTTYAISSLSPVALTEHSCPYGEVLECHDPLPAKLAQEEEQKPEPRLSQKLAQVGTKLLKVPLMLGFLYLFVCSLDVLSSAFQLAGGKVAGDIFKDNAILSNPVAGLVVGILVTVLVQSSSTSTSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHVTGLVVASFNIRGGRDAPDLLKVITEPFTKLIIQLDKSVITSIAVGDESLRNHSLIRIWCQPETKEASTSMSRVEAIGSLANTTMEKCNHIFVDTGLPDLAVGLILLAGSLVVLCTCLILLVKMLNSLLKGQVANVIQKVINTDFPAPFTWVTGYFAMVVGASMTFVVQSSSVFTSAITPLIGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSSFQIALCHFFFNISGILLWYPLPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQAMVGVGTPFGALLAFVVLVNVLQSRSPGHLPKWLQTWDFLPRWMHSLQPLDGLITRATLCYARPEPRSPQLPPRVFLEELPPATPSPRLALPAHHNATRL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
298	N-linked (GlcNAc...) asparagine			UniProt
328	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Surfactant metabolism	Rattus norvegicus
Type II Na+/Pi cotransporters	Rattus norvegicus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026