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Neurexin-3

Summary

UniProt ID: Q07310
Gene Symbol: Nrxn3
Gene ID: 116508
Organism: Rattus norvegicus (Norway rat)

External Links

RaftProt: Q07310
Re-Glyco: Q07310

Annotation

Keyword: Alternative splicing Calcium Cell adhesion Cell membrane Cell projection Direct protein sequencing Disulfide bond EGF-like domain Heparan sulfate Metal-binding Reference proteome Repeat Signal Synapse Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	Reference
cell adhesion
chemical synaptic transmission	ISO	GO_REF
neurotransmitter secretion	ISO	GO_REF
synapse assembly	ISO	GO_REF
synapse assembly	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

trans-synaptic signaling, modulating synaptic transmission

cell adhesion

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

postsynaptic specialization assembly [inference]

postsynaptic density assembly

postsynaptic specialization organization [inference]

postsynaptic density organization [inference]

postsynaptic density assembly

postsynaptic specialization assembly [inference]

postsynaptic density assembly

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

organelle assembly [inference]

postsynaptic specialization assembly [inference]

postsynaptic density assembly

presynapse assembly

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization [inference]

synapse assembly

presynapse organization [inference]

presynapse assembly

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning

behavior [inference]

learning or memory [inference]

learning

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to membrane [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to postsynapse [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein localization to cell periphery [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

protein-containing complex localization [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

establishment of localization [inference]

transport [inference]

neurotransmitter transport [inference]

neurotransmitter secretion

secretion [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

export from cell [inference]

secretion by cell [inference]

signal release [inference]

signal release from synapse [inference]

neurotransmitter secretion

establishment of localization in cell [inference]

neurotransmitter secretion

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to postsynaptic membrane [inference]

protein localization to postsynaptic specialization membrane [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

receptor localization to synapse [inference]

neurotransmitter receptor localization to postsynaptic specialization membrane

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

trans-synaptic signaling, modulating synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of biological quality [inference]

regulation of postsynaptic membrane neurotransmitter receptor levels

neurotransmitter receptor localization to postsynaptic specialization membrane

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
protein-containing complex	ISO	GO_REF
slit diaphragm
presynaptic membrane	ISS	GO_REF
presynaptic membrane	ISO	GO_REF
presynaptic membrane	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex

trans-synaptic protein complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

anchoring junction [inference]

cell-cell junction [inference]

filtration diaphragm [inference]

slit diaphragm

Displaying **all 2** entries
GO Term	Evidence Code	Reference
calcium channel regulator activity	ISO	GO_REF
metal ion binding

GO Hierarchy

molecular function

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

calcium channel regulator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSFTLHSVFFTLKVSSFLGSLVGLCLGLEFMGLPNQWARYLRWDASTRSDLSFQFKTNVSTGLLLYLDDGGVCDFLCLSLVDGRVQLRFSMDCAETTVLSNKQVNDSSWHFLMVSRDRVRTGLVIDGEGQSGELRAQRPYMDVVSDLFLGGGPADIRPSALTLDGVQNMPGFKGLMLDLKYGNSEPRLLGSQSVQLEAEGPCGERPCENGGICFLLDGHPTCDCSTTGYGGTLCSEDVSQGPGLSHLMMSEQGRSKAREENVATFRGSEYLSYDLSQNPIQSSSSEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDSSYVGPSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGATKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILLTHGKPQERKDVRSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGQSEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKVIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLTLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNNFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIDRGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGVLVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGANATLQVDNWPVNEHYPTGNTDNERRQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSVSGTTHTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRSDKSLSTSIFEGGYKAHAPKWESKDFRPNKVSETSRTTTTSLSPELIRFTASSSSGMVPKLPAGKMNNRDLKPQPDIVLLPLPTAYELDSTKLKSPLITCPMFRNVPTANPTEPGIRRVPGASEVIRESNSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQASSKSGHKKQKNKDKEYYV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
58	N-linked (GlcNAc...) asparagine	UniProt
105	N-linked (GlcNAc...) asparagine	UniProt
761	N-linked (GlcNAc...) asparagine	UniProt
1193	N-linked (GlcNAc...) asparagine	UniProt
1291	N-linked (GlcNAc...) asparagine	UniProt
1335	N-linked (GlcNAc...) asparagine	UniProt
1351	O-linked (Xyl...) (heparan sulfate) serine	UniProt
1500	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Neurexins and neuroligins	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements