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C-X-C chemokine receptor type 4

Summary

UniProt ID: Q07FZ4
Gene Symbol: cxcr4 TGas094c16.1
Gene ID: 100038176
Organism: Xenopus tropicalis (tropical clawed frog)

External Links

PubChem: Q07FZ4
Re-Glyco: Q07FZ4

Annotation

Keyword: Cell membrane Cytoplasm Disulfide bond G-protein coupled receptor Gastrulation Glycoprotein Nucleus Reference proteome Sulfation Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
immune response	IBA	GO_REF
G protein-coupled receptor signaling pathway	ISS	GO_REF
G protein-coupled receptor signaling pathway	IEA	GO_REF
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISS	GO_REF
positive regulation of cytosolic calcium ion concentration	IBA	GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cell development [inference]

hemopoiesis [inference]

definitive hemopoiesis

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

mesodermal cell migration [inference]

mesoderm migration involved in gastrulation

cell migration involved in gastrulation [inference]

mesoderm migration involved in gastrulation

multicellular organismal process [inference]

tissue migration [inference]

mesoderm migration involved in gastrulation

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

hemopoiesis [inference]

definitive hemopoiesis

animal gross anatomical part developmental process [inference]

animal organ development [inference]

brain development

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cell development [inference]

hemopoiesis [inference]

definitive hemopoiesis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

response to stimulus [inference]

immune response

response to chemical [inference]

response to peptide [inference]

response to cytokine [inference]

cellular response to cytokine stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
nucleus	ISS	GO_REF
nucleus	IEA	GO_REF
lysosome	ISS	GO_REF
early endosome	ISS	GO_REF
late endosome	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	Reference
C-C chemokine receptor activity	IBA	GO_REF
C-X-C chemokine receptor activity	ISS	GO_REF
C-C chemokine binding	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding [inference]

chemokine binding [inference]

C-C chemokine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled chemoattractant receptor activity [inference]

chemokine receptor activity [inference]

immune receptor activity [inference]

cytokine receptor activity [inference]

chemokine receptor activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MDGFSGGIDINIFDSNSTENGSGDFEDFSEPCFMHDNSDFNRIFLPTIYSFIFLLGIIGNGLVVVVMGYQKKSRTMTDKYRLHLSVADLLFVFTLPFWSVDAAIGWYFKEFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQGSRKMLADKVVYAGVWLPALLLTVPDLVFARVSDENGQFVCDRIYPIDNRETWTVGFRFLHITVGLILPGLIILICYCVIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYVCLTTDTFMLLGLLKADCIWENTLHKAISITEALAFFHCCLNPILYAFLGAKFKTSAQNAFTSVSRGSSLKILSKKRAGLSSVSTESESSSFHSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
16	N-linked (GlcNAc...) asparagine			UniProt
20	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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