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Testican-1

Summary

UniProt ID: Q08629
Gene Symbol: SPOCK1 SPOCK TIC1 TICN1
Gene ID: 6695
Organism: Homo sapiens (human)

External Links

GlyConnect

Testican-1

GlyGen

Q08629

Re-Glyco

Q08629

Annotation

Keyword: Direct protein sequencing Disulfide bond Extracellular matrix Heparan sulfate Proteomics identification Reference proteome Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
regulation of cell growth	NAS	PMID
neuron migration	ISS	GO_REF
cell adhesion	NAS	PMID
nervous system development	NAS	PMID
negative regulation of cell-substrate adhesion	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

neuron differentiation [inference]

central nervous system neuron differentiation

cell motility [inference]

cell migration [inference]

neuron migration

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

neuron differentiation [inference]

central nervous system neuron differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of cell growth

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of cellular process [inference]

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion

regulation of cell-substrate adhesion [inference]

negative regulation of cell-substrate adhesion

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of cellular component organization [inference]

regulation of cell growth

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
obsolete extracellular space
cytoplasm	ISS	GO_REF
postsynaptic density	NAS	PMID
sarcoplasm	ISS	GO_REF
extracellular matrix	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

sarcoplasm

cell junction [inference]

synapse [inference]

neuromuscular junction

external encapsulating structure [inference]

extracellular matrix

node of Ranvier

organelle [inference]

postsynaptic specialization [inference]

postsynaptic density

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
serine-type endopeptidase inhibitor activity	NAS	PMID
cysteine-type endopeptidase inhibitor activity	IDA	PMID
extracellular matrix structural constituent	HDA	PMID
calcium ion binding	IDA	PMID
calcium ion binding	IBA	GO_REF

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

collagen binding

extracellular matrix binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRFRDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTSILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAVTEDDEDEDDDKEDEVGYIW

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
65		23584533 25813380		GlyGen
96		23584533	G57321FI	GlyGen
126		23584533	G57321FI	GlyGen
131		23584533	G57321FI	GlyGen
224		23584533	G57321FI	GlyGen
228	O-linked (GalNAc...) threonine	23234360 23584533	G29931IJ G43417UB G57321FI	UniProt GlyGen GlyConnect
286		23090970 24190977		GlyGen
383	O-linked (Xyl...) (glycosaminoglycan) serine			UniProt GlyGen
388	O-linked (Xyl...) (glycosaminoglycan) serine			UniProt GlyGen