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ATP-binding cassette sub-family B member 6

Summary

UniProt ID: Q08D64
Gene Symbol: abcb6
Gene ID: 780100
Organism: Xenopus tropicalis (tropical clawed frog)

External Links

Re-Glyco: Q08D64

Annotation

Keyword: ATP-binding Cell membrane Disulfide bond Endoplasmic reticulum Endosome Glycoprotein Golgi apparatus Lysosome Mitochondrion outer membrane Reference proteome Secreted Translocase Transmembrane helix Transport

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
porphyrin-containing compound metabolic process	ISS	GO_REF
intracellular copper ion homeostasis	ISS	GO_REF
tetrapyrrole metabolic process	ISS	GO_REF
heme transmembrane transport	ISS	GO_REF
heme metabolic process	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

tetrapyrrole metabolic process

porphyrin-containing compound metabolic process

heme metabolic process

pigment metabolic process [inference]

heme metabolic process

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

pigment granule organization [inference]

melanosome organization [inference]

melanosome assembly

organelle assembly [inference]

melanosome assembly

cellular component assembly [inference]

organelle assembly [inference]

melanosome assembly

cellular detoxification [inference]

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular copper ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular copper ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular copper ion homeostasis

copper ion homeostasis [inference]

intracellular copper ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular copper ion homeostasis

inorganic ion homeostasis [inference]

copper ion homeostasis [inference]

intracellular copper ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

iron coordination entity transport [inference]

heme transport [inference]

heme transmembrane transport

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

heme transmembrane transport

nitrogen compound transport [inference]

heme transport [inference]

heme transmembrane transport

detoxification [inference]

detoxification of inorganic compound [inference]

detoxification of cadmium ion [inference]

cellular detoxification of cadmium ion

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

cellular detoxification [inference]

cellular detoxification of metal ion [inference]

cellular detoxification of cadmium ion

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	Reference
Golgi membrane	ISS	GO_REF
Golgi membrane	IEA	GO_REF
mitochondrion	ISS	GO_REF
mitochondrion	IEA	GO_REF
mitochondrial outer membrane	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

late endosome membrane

multivesicular body membrane

endolysosome membrane

pigment granule membrane [inference]

melanosome membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endolysosome membrane

endosome membrane [inference]

early endosome membrane

late endosome membrane

multivesicular body membrane

endolysosome membrane

organelle outer membrane [inference]

mitochondrial outer membrane

pigment granule membrane [inference]

melanosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
ATP binding	ISS	GO_REF
ATP binding	IEA	GO_REF
ABC-type heme transporter activity	ISS	GO_REF
ABC-type heme transporter activity	IEA	GO_REF
ATP hydrolysis activity	ISS	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

heme transmembrane transporter activity [inference]

ABC-type heme transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity

ABC-type heme transporter activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

tetrapyrrole binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity

ABC-type heme transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MVRLGSYCEHNGSISQAWLDSGLSPCFYFTLVPSVLLSFSFLLGALQSALYARHSTTMEPKYIPRSRLYRLQIVLSVVLILQSVIGLIWQAAGTDVVYGYMIVHGCLSVVAWGFSLWLLHLERTRALVREKSRGHGVVLLLFWALAFAAENLAFISWQSPNWWWLSRDTVPQKVQFGLWITRYVCTLFLFVLGIRAPGRPRKPYIVLINEDERDVETSQPLLRDPNQSTWQGFKKKLLLVMQYIWPRRNIPLQLLVALCMGLMGLERAINVFVPIYAKKIVDGLTEDSTWNILAVTVCIYVLLKFLQGGGAGTTGFLSNLRTFMWIRVQQFTNREVQIRLFAHLHSLSLRWHLGRKTGEVLRSVDRGTSSINSLLSYIVFSILPTIADIVIGIVYFTSSFNAWFGLIIFVCMTLYLTLTIIITEWRTKYRREMNTRDNEAKSRAVDSLLNFETVKYYNAEGYEVGRFNDSIMKYQVSEWKVNASLAMLNQTQNLIIGLGLLAGSLLCAYFVTENKFKVGDYVLFGTYIIQLYTPLNWFGTYYRMIQSSFIDMENMFELFNEDQEVKDAVNAPALMFRSGKIEFENVHFSYLDGKEILRDISFTVMPGQSIALVGPSGSGKSTIIRLLFRFYDVKGGTIKVDGQDISTVRQESLRSHIGVVPQDTVLFNDTIRNNIRYGRVSATDDEVEEAAAAADIHERILSFRDGYDTQTGERGLKLSGGEKQRVAIARTILKAPQIILLDEATSALDTETERNIQASLAKVCANRTTIVVAHRLSTVINSDQILVLKEGQIVERGRHEELLLKGGVYAGMWQKQQSGSESSSDSDSERKDRTSEKLQPPKATPRRGH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites