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5-hydroxytryptamine receptor 1A

Summary

UniProt ID: Q0EAB6
Gene Symbol: HTR1A
Gene ID: 100009683
Organism: Equus caballus (horse)

External Links

Re-Glyco: Q0EAB6

Annotation

Keyword: Behavior Cell membrane Cell projection Disulfide bond G-protein coupled receptor Glycoprotein Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **11 - 15** of 22 in total

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GO Term	Evidence Code	Reference
regulation of serotonin secretion	ISS	GO_REF
regulation of serotonin secretion	IEA	GO_REF
regulation of vasoconstriction	IEA	GO_REF
adult behavior
exploration behavior	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting serotonin receptor signaling pathway

G protein-coupled serotonin receptor signaling pathway [inference]

adenylate cyclase-inhibiting serotonin receptor signaling pathway

serotonin receptor signaling pathway

metabolic process [inference]

phenol-containing compound metabolic process [inference]

serotonin metabolic process

indole-containing compound metabolic process [inference]

serotonin metabolic process

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction

behavior [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of hormone secretion

signaling [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of serotonin secretion

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting serotonin receptor signaling pathway

G protein-coupled serotonin receptor signaling pathway [inference]

adenylate cyclase-inhibiting serotonin receptor signaling pathway

serotonin receptor signaling pathway

regulation of cell communication [inference]

regulation of hormone secretion

regulation of metabolic process [inference]

regulation of amine metabolic process [inference]

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process

regulation of primary metabolic process [inference]

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process

regulation of secretion by cell [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction

regulation of behavior

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISS	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF GO_REF
dendrite	IBA	GO_REF
dendrite	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
Gi/o-coupled serotonin receptor activity	IEA	GO_REF
G protein-coupled serotonin receptor activity	ISS	GO_REF
G protein-coupled serotonin receptor activity	IBA	GO_REF
G protein-coupled serotonin receptor activity	IEA	GO_REF GO_REF
neurotransmitter receptor activity	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor-receptor interaction

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

serotonin binding

heterocyclic compound binding [inference]

serotonin binding

amine binding [inference]

serotonin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled amine receptor activity [inference]

G protein-coupled serotonin receptor activity

Gi/o-coupled serotonin receptor activity

serotonin receptor activity

neurotransmitter receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MDVLGPGQGNNTTSSEGPFGTRANATGISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLVGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGADSRLGASPAPQRKKSANGELGSREWRQGVENKAGGVLCANGAVRQGDDGAALEVIEVHRMGNSKEHLPLPSEAGAIPCAPAFFEKKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKILKCKFCRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
10	N-linked (GlcNAc...) asparagine	UniProt
11	N-linked (GlcNAc...) asparagine	UniProt
24	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements