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Myoblast growth factor receptor egl-15

Summary

UniProt ID: Q10656
Gene Symbol: F58A3.2 egl-15
Gene ID: 181291
Organism: Caenorhabditis elegans

External Links

PubChem: Q10656
Re-Glyco: Q10656

Annotation

Keyword: ATP-binding Alternative splicing Developmental protein Disulfide bond Glycoprotein Immunoglobulin domain Magnesium Metal-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
nematode larval development	IMP	PMID
muscle organ development	IMP	PMID
positive regulation of cell population proliferation	IBA	GO_REF
fibroblast growth factor receptor signaling pathway	IMP	PMID
fibroblast growth factor receptor signaling pathway	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

cell motility [inference]

cell migration

reproductive process [inference]

multicellular organismal reproductive process [inference]

reproductive behavior [inference]

egg-laying behavior

multicellular organismal process [inference]

multicellular organism development [inference]

larval development [inference]

nematode larval development

behavior [inference]

reproductive behavior [inference]

egg-laying behavior

post-embryonic development [inference]

larval development [inference]

nematode larval development

developmental process [inference]

anatomical structure morphogenesis [inference]

tube morphogenesis [inference]

digestive tract morphogenesis

anatomical structure development [inference]

multicellular organism development [inference]

larval development [inference]

nematode larval development

animal organ development [inference]

muscle organ development

muscle structure development [inference]

muscle organ development

homeostatic process [inference]

cellular homeostasis [inference]

muscle cell cellular homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of cellular component organization [inference]

regulation of cell projection organization

regulation of biological quality [inference]

regulation of protein stability

Displaying **all 2** entries
GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF
signaling receptor complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
protein kinase activity	IDA	PMID
protein kinase activity	IEA	GO_REF
transmembrane receptor protein tyrosine kinase activity	IBA	GO_REF
transmembrane receptor protein tyrosine kinase activity	IEA	GO_REF
ATP binding	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSYFLASCLGVGLLSTVSCSLQGLTSHYRENIPRFKHVANERYEVFLGDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLWSCRVHNAYGQISRNFTVEVIDFCDYFLFPDIHHLNIPMECVCLWKYNKEAKRSDVNYAAVTGEVCSKYASRMINRARKPLPMIPCFGDHCKEFDTTPVSDFGLPGKPEDDPLVKRVVLKKDDVIVPVHDSEESPSESRTEFINADEKENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACLSGNSLGMSMANATLTVNEFMAIHLLTGDEPKIDRWTTSDYIFTTILLFLLLAATLFGILFMVCKQTLHKKGFMDDTVGLVARKKRVVVSKRPMNEDNENSDDEPSPYQIQIIETPITKKEAARKQRKRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWMLTMTNETIEGSQEFNDQFFSERSTASGPVSPMESFQKKRKHRPLSAPVNLPSEPQHTICDDYESNFSVEPPNDPNHLYCNDNMLKNHIITPETSQRIPSNNNSMSKPEF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	Source
121	N-linked (GlcNAc...) asparagine	UniProt
280	N-linked (GlcNAc...) asparagine	UniProt
299	N-linked (GlcNAc...) asparagine	UniProt
401	N-linked (GlcNAc...) asparagine	UniProt
407	N-linked (GlcNAc...) asparagine	UniProt
433	N-linked (GlcNAc...) asparagine	UniProt
440	N-linked (GlcNAc...) asparagine	UniProt
449	N-linked (GlcNAc...) asparagine	UniProt
474	N-linked (GlcNAc...) asparagine	UniProt
497	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 29 in total

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Pathway Name	Organism
FGFR1b ligand binding and activation	Caenorhabditis elegans
FGFR1c ligand binding and activation	Caenorhabditis elegans
FGFR2b ligand binding and activation	Caenorhabditis elegans
FGFR2c ligand binding and activation	Caenorhabditis elegans
FGFR3b ligand binding and activation	Caenorhabditis elegans
FGFR3c ligand binding and activation	Caenorhabditis elegans
FGFR4 ligand binding and activation	Caenorhabditis elegans
FRS-mediated FGFR1 signaling	Caenorhabditis elegans
FRS-mediated FGFR2 signaling	Caenorhabditis elegans
FRS-mediated FGFR3 signaling	Caenorhabditis elegans

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080001	bone disease	Alliance of Genome Resources

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