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Angiotensin-converting enzyme

Summary

UniProt ID: Q10714
Gene Symbol: ACE ANCE AnCE Ance BG:DS08220.3 CG8827 Dmel\CG8827 Dmel_CG8827 RACE Race ance anon-EST:fe3D10 race
Gene ID: 34805
Organism: Drosophila melanogaster (fruit fly)

External Links

GlyGen: Q10714
Re-Glyco: Q10714

Annotation

Keyword: 3D-structure Carboxypeptidase Disulfide bond Glycoprotein Metal-binding Metalloprotease Reference proteome Secreted Signal Zinc

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
proteolysis	IDA	PMID PMID PMID PMID PMID PMID PMID PMID PMID
proteolysis	IEA	GO_REF
metamorphosis	IEP	PMID
mating	IEP	PMID
response to symbiotic bacterium	IEP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

hormone metabolic process [inference]

peptide hormone processing

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

reproductive process [inference]

multi-organism reproductive process [inference]

mating

multicellular organismal process [inference]

multicellular organism development [inference]

metamorphosis

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

metamorphosis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to symbiont [inference]

response to symbiotic bacterium

response to bacterium [inference]

response to symbiotic bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to symbiont [inference]

response to symbiotic bacterium

response to bacterium [inference]

response to symbiotic bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to symbiont [inference]

response to symbiotic bacterium

response to bacterium [inference]

response to symbiotic bacterium

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing

Displaying **all 2** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
plasma membrane	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
carboxypeptidase activity
metallopeptidase activity	IDA	PMID
metallopeptidase activity	IBA	GO_REF
metallopeptidase activity	IEA	GO_REF
peptidyl-dipeptidase activity	IDA	PMID PMID PMID PMID PMID PMID PMID PMID PMID PMID

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRLFLLALLATLAVTQALVKEEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWLDEYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSNKCVSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	Source
53	N-linked (GlcNAc...) asparagine	8761461	UniProt GlyGen
196	N-linked (GlcNAc...) asparagine	8761461	UniProt GlyGen
311	N-linked (GlcNAc...) asparagine	8761461	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Metabolism of Angiotensinogen to Angiotensins	Drosophila melanogaster

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements