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Thyrotropin-releasing hormone-degrading ectoenzyme

Summary

UniProt ID: Q10836
Gene Symbol: Trhde
Gene ID: 366894
Organism: Rattus norvegicus (Norway rat)

External Links

PubChem: Q10836
Re-Glyco: Q10836

Annotation

Keyword: Aminopeptidase Direct protein sequencing Disulfide bond Glycoprotein Metal-binding Metalloprotease Phosphoprotein Reference proteome Signal-anchor Transmembrane helix Zinc

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
proteolysis	TAS	PMID
proteolysis	IBA	GO_REF
proteolysis	IEA	GO_REF
peptide catabolic process	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

peptide metabolic process [inference]

peptide catabolic process

catabolic process [inference]

peptide catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

Displaying **all 2** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

Displaying **all 5** entries
GO Term	Evidence Code	Reference
aminopeptidase activity	TAS	PMID
aminopeptidase activity	IEA	GO_REF
zinc ion binding	IEA	GO_REF
pyroglutamyl-peptidase activity	IEA	GO_REF
metalloaminopeptidase activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

cysteine-type peptidase activity [inference]

pyroglutamyl-peptidase activity

metallopeptidase activity [inference]

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

omega peptidase activity [inference]

pyroglutamyl-peptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

cysteine-type peptidase activity [inference]

pyroglutamyl-peptidase activity

metallopeptidase activity [inference]

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

omega peptidase activity [inference]

pyroglutamyl-peptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MALDGERGEQEEEKKKKKKKKKRKKKEEEGAEKSSSPFAATMGEDDAALRASGRGLSDPWADSVGVRPRTTERHIAVHKRLVLAFAVSIVALLAVTMLAVLLSLRFDECGASAAMPGTDGGLGGFPERGGNSSYPGSARRNHHAGEESSQREIGEVGTAGTPSAHPPSEEEQEQWQPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACQNATRYVVLHASRVAVEKVQVAEDRAFGAVPVAGFFLYPQTQVLVVVLNRTLDAQRHYNLKIIYNALIENELLGFFRSSYVIHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPSWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLRATDIDKVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNMTAENRILITQQHFIYDIGAKTKALQLQNSSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITYLDKGSWILGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMENYNIFNEYILKQVATTYSKLGWPKNNFNGSVVQASYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRNLLSRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMKSYDGVASASFSRAVETVEANVRWKRLYQDELFQWLGKAMRH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

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Position	Description	Source
131	N-linked (GlcNAc...) asparagine	UniProt
202	N-linked (GlcNAc...) asparagine	UniProt
217	N-linked (GlcNAc...) asparagine	UniProt
264	N-linked (GlcNAc...) asparagine	UniProt
380	N-linked (GlcNAc...) asparagine	UniProt
647	N-linked (GlcNAc...) asparagine	UniProt
676	N-linked (GlcNAc...) asparagine	UniProt
691	N-linked (GlcNAc...) asparagine	UniProt
705	N-linked (GlcNAc...) asparagine	UniProt
726	N-linked (GlcNAc...) asparagine	UniProt