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MIRAGE
Probable ferric reductase transmembrane component 8

Summary
UniProt ID
Q12209
Gene Symbol
  • FRE8
  • L2114
  • YLR047C
Gene ID
850736
Organism
Saccharomyces cerevisiae S288C
Re-Glyco
Q12209
Annotation
Keyword
  • Electron transport
  • FAD
  • Glycoprotein
  • Iron transport
  • NAD
  • Oxidoreductase
  • Reference proteome
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 3 entries
GO Term
plasma membrane
endoplasmic reticulum
fungal-type vacuole membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MNLKSIVSWFKEHLPSFDVDVDKHFRTLRVRKYSQICLLISFIIICVIIPLMNYLLLTDKFFKICHHLKHHVFNRRSWVHKTHMYHKQSLQLCLICFVFTSFFVIQGANGDLLEITKRMGRISVALMPPLLFLTLRPSPLPHTLYLALLPLHKWISRIVVLESILHTWFYLYYMYINDTLYVKMRKLPNIYGVIALGLFLLIAITSVRYARRWSYRVFYYVHYVSTWLILVFLHYHARPGISYYTTLNVLILTGQIVYRLHITNVTRVTIVPISSSLSLLEFPLTDLPKKPILPGGHLRINIYHRNFLRRFFSHLIPFQHPFTIASIPSDNLVRLIIRNGHFPLRTNEKYYITGAFEPELSFISKPTVPFNITTKSSKNPFRNNSSALINSPLNFLIKAQRVFMCVGGSGISFGLPLLRILNFNGVNVRLLWVSRDYKDLEVLNHFKNNFEGMEIYISGTEGNEQDIEIDYIDYHDCAADINDEVRSISSSGRVSELGDNSMLSDGNPQPTEPNENTALLSKKSTLRNHHPPKTSDIPDINADDEIDFTYAFSRSKSRKNTAQGTLTTHSSFNGSSVFRQPKIIEPPAQDPCLEAAPKKIRIPAGVKVFFGRPTLGDKDYEWCLQTECDAETDSIQCCRWANQGRDHAEYLSQVWVLAAGPRGLIESTKRWATDGGLHFHGESFAL
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
371 N-linked (GlcNAc...) asparagine
383 N-linked (GlcNAc...) asparagine
384 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Detoxification of Reactive Oxygen Species Saccharomyces cerevisiae
Neutrophil degranulation Saccharomyces cerevisiae
Thyroxine biosynthesis Saccharomyces cerevisiae
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025