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MIRAGE
FAS-associated death domain protein
Summary
- UniProt ID
- Q13158
- Gene Symbol
-
- FADD
- GIG3
- MORT1
- Gene ID
- 8772
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Apoptosis
- Disease variant
- Glycoprotein
- Host-virus interaction
- Innate immunity
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| cell body |
| cytosol |
| cytoplasmic side of plasma membrane |
| death-inducing signaling complex |
| CD95 death-inducing signaling complex |
| ripoptosome |
Sequence
MDPFLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGAMSPMSWNSDASTSEAS
Glycosylation Sites
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CASP8 activity is inhibited | Homo sapiens |
| Defective RIPK1-mediated regulated necrosis | Homo sapiens |
| Dimerization of procaspase-8 | Homo sapiens |
| FasL/ CD95L signaling | Homo sapiens |
| Ligand-dependent caspase activation | Homo sapiens |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | Homo sapiens |
| RIPK1-mediated regulated necrosis | Homo sapiens |
| Regulation by c-FLIP | Homo sapiens |
| Regulation of TNFR1 signaling | Homo sapiens |
| Regulation of necroptotic cell death | Homo sapiens |
