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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Growth factor receptor-bound protein 7
Summary
- UniProt ID
- Q14451
- Gene Symbol
-
- GRB7
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell junction
- Cell membrane
- Cell projection
- Cytoplasm
- Lipid-binding
- Phosphoprotein
- RNA-binding
- Reference proteome
- Repressor
- SH2 domain
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of cell migration |
| negative regulation of translation |
| epidermal growth factor receptor signaling pathway |
| stress granule assembly |
| GO Term |
|---|
| plasma membrane |
| cell projection |
| cytosol |
| focal adhesion |
| cytoplasmic stress granule |
| GO Term |
|---|
| phosphatidylinositol binding |
| RNA binding |
| protein kinase binding |
| identical protein binding |
Sequence
MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 23 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream signal transduction | Homo sapiens |
| GRB7 events in ERBB2 signaling | Homo sapiens |
| RET signaling | Homo sapiens |
| RND1 GTPase cycle | Homo sapiens |
| Signaling by SCF-KIT | Homo sapiens |
| Tie2 Signaling | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
