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Semaphorin-3A

Summary

UniProt ID

Q14563

Gene Symbol

SEMA3A
SEMAD

Organism

Homo sapiens (human)

External Links

GlyGen: Q14563
PubChem: Q14563
The O-GlcNAc Database: Q14563
O-GlcNAcAtlas: Q14563

Annotation

Keyword

Developmental protein
Differentiation
Disease variant
Disulfide bond
Glycoprotein
Hypogonadotropic hypogonadism
Immunoglobulin domain
Kallmann syndrome
Neurogenesis
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 25 in total

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GO Term
negative regulation of neuron projection development
nerve development
olfactory bulb development
sympathetic nervous system development
sensory system development
sympathetic ganglion development
neural crest cell migration involved in autonomic nervous system development
positive regulation of neuron migration
regulation of axon extension involved in axon guidance
negative regulation of axon extension involved in axon guidance

Displaying **all 6** entries
GO Term
extracellular region
extracellular space
plasma membrane
axon
dendrite
glutamatergic synapse

Displaying **all 3** entries
GO Term
semaphorin receptor binding
chemorepellent activity
neuropilin binding

Annotation information from UniProt.

Sequence

MGWLTRIVCLFWGVLLTARANYQNGKNNVPRLKLSYKEMLESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFDLVNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKAYNQTHLYACGTGAFHPICTYIEIGHHPEDNIFKLENSHFENGRGKSPYDPKLLTASLLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPKFISAHLISESDNPEDDKVYFFFRENAIDGEHSGKATHARIGQICKNDFGGHRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNFKDPKNPVVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGPYAHRDGPNYQWVPYQGRVPYPRPGTCPSKTFGGFDSTKDLPDDVITFARSHPAMYNPVFPMNNRPIVIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYDLEEVLLEEMTVFREPTAISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYCAWDGSACSRYFPTAKRRTRRQDIRNGDPLTHCSDLHHDNHHGHSPEERIIYGVENSSTFLECSPKSQRALVYWQFQRRNEERKEEIRVDDHIIRTDQGLLLRSLQQKDSGNYLCHAVEHGFIQTLLKVTLEVIDTEHLEELLHKDDDGDGSKTKEMSNSMTPSQKVWYRDFMQLINHPNLNTMDEFCEQVWKRDRKQRRQRPGHTPGNSNKWKHLQENKKGRNRRTHEFERAPRSV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	GlyTouCan ID	Source
53	N-linked (GlcNAc...) asparagine		UniProt GlyGen
125	N-linked (GlcNAc...) asparagine		UniProt GlyGen
228		G49108TO G70994MS	GlyGen The O-GlcNAc Database
590	N-linked (GlcNAc...) asparagine	G80920RR	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
CRMPs in Sema3A signaling	Homo sapiens
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	Homo sapiens
Sema3A PAK dependent Axon repulsion	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements