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MIRAGE
Transforming growth factor-beta-induced protein ig-h3

Summary
UniProt ID
Q15582
Gene Symbol
  • BIGH3
  • TGFBI
Gene ID
7045
Organism
Homo sapiens (human)
GlyGen
Q15582
PubChem
Q15582
The Human Metabolome Database
HMDBP07469
RaftProt
Q15582
Re-Glyco
Q15582
Annotation
Keyword
  • 3D-structure
  • Amyloid
  • Amyloidosis
  • Cell adhesion
  • Corneal dystrophy
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Extracellular matrix
  • Gamma-carboxyglutamic acid
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Signal
  • Vision
Gene Ontology (GO)
Displaying all 8 entries
GO Term
extracellular region
basement membrane
extracellular space
plasma membrane
extracellular matrix
collagen-containing extracellular matrix
trans-Golgi network
extracellular exosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRKYFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTITNNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTPPIDAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCIAAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQASAFSRASQRSVRLAPVYQKLLERMKH
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
28
656
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Amyloid fiber formation Homo sapiens
Disease
Displaying all 6 entries
DO ID Disease Name Source
DOID:0060444 granular corneal dystrophy 2
DOID:0060447 epithelial basement membrane dystrophy
DOID:0060453 Reis-Bucklers corneal dystrophy
DOID:0060455 Thiel-Behnke corneal dystrophy
DOID:0080530 granular corneal dystrophy 1
DOID:2566 corneal dystrophy
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025