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Transcription factor E2F4

Summary

UniProt ID

Q16254

Gene Symbol

E2F4

Organism

Homo sapiens (human)

External Links

GlyGen: Q16254
PubChem: Q16254
The O-GlcNAc Database: Q16254

Annotation

Keyword

3D-structure
Acetylation
Activator
Cell cycle
Cilium biogenesis/degradation
DNA-binding
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
epithelial cell development
regulation of transcription by RNA polymerase II
positive regulation of transcription by RNA polymerase II
centriole assembly
cell volume homeostasis
cell cycle
blood circulation
animal organ morphogenesis
regulation of cell population proliferation
motile cilium assembly

Displaying **all 4** entries
GO Term
nucleoplasm
RNA polymerase II transcription regulator complex
chromatin
cytoplasm

Displaying **all 10** entries
GO Term
DNA binding
sequence-specific double-stranded DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
promoter-specific chromatin binding
protein domain specific binding
protein dimerization activity
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity

Annotation information from UniProt.

Sequence

MAEAGPQAPPPPGTPSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVLEGIGLIEKKSKNSIQWKGVGPGCNTREIADKLIELKAEIEELQQREQELDQHKVWVQQSIRNVTEDVQNSCLAYVTHEDICRCFAGDTLLAIRAPSGTSLEVPIPEGLNGQKKYQIHLKSVSGPIEVLLVNKEAWSSPPVAVPVPPPEDLLQSPSAVSTPPPLPKPALAQSQEASRPNSPQLTPTAVPGSAEVQGMAGPAAEITVSGGPGTDSKDSGELSSLPLGPTTLDTRPLQSSALLDSSSSSSSSSSSSSNSNSSSSSGPNPSTSFEPIKADPTGVLELPKELSEIFDPTRECMSSELLEELMSSEVFAPLLRLSPPPGDHDYIYNLDESEGVCDLFDVPVLNL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Cyclin A:Cdk2-associated events at S phase entry	Homo sapiens
Cyclin D associated events in G1	Homo sapiens
Cyclin E associated events during G1/S transition	Homo sapiens
G0 and Early G1	Homo sapiens
G1/S-Specific Transcription	Homo sapiens
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Homo sapiens
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	Homo sapiens
Transcription of E2F targets under negative control by DREAM complex	Homo sapiens
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	Homo sapiens