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Semaphorin-1A

Summary

UniProt ID: Q17330
Gene Symbol: smp-1 Y54E5B.1 sema-1a
Gene ID: 173351
Organism: Caenorhabditis elegans

External Links

Re-Glyco: Q17330

Annotation

Keyword: Developmental protein Differentiation Disulfide bond Glycoprotein Neurogenesis Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
neural crest cell migration	IBA	GO_REF
axon guidance	IBA	GO_REF
positive regulation of cell migration	IBA	GO_REF
negative chemotaxis	IBA	GO_REF
semaphorin-plexin signaling pathway	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

semaphorin-plexin signaling pathway

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

reproductive process [inference]

developmental process involved in reproduction [inference]

genitalia morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

genitalia morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

genitalia morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

sensory organ morphogenesis [inference]

nematode male tail mating organ morphogenesis

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

nematode male tail mating organ morphogenesis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

negative chemotaxis

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

semaphorin-plexin signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

Displaying 1 entry
GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	Reference
semaphorin receptor binding	IBA	GO_REF
semaphorin receptor binding	IPI	PMID
semaphorin receptor binding	IEA	GO_REF
chemorepellent activity	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

semaphorin receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

chemorepellent activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

chemorepellent activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRRILTLLLLFNVVRSSEAITGGVVNLRPKQIINSVGIGDRFGGIGTSSDESDHFKLLAADGDSLLVGARNAVYNLSLSTLSVNHKIDWKPPAEHIEECIMKGKSKTDCQNYIRVLARKSAGVSLVCGTHAFSPKCREYTVTEFGIRNTRQFDGQGISPYDPKHNSSALYVPGTNQLFVATVTDFVGNDALIYRKTIDETPSSKSAANIRTQSYDARVLNAPNFVATFAYKEHVYFWFREIASEAIDNNEEPQIYARVARVCKNDKGGARPANERWTSYLKARLNCSLPSGSSPFYFNELKAVSDPIDAGNNNHVVYTVFSTPDSDVRMSAVCKFSMKKIREEFDNGTFKHQNNAQSMWMAFNRNEVPKPRPGSCSPDSTKLPENTVSFILHHPLLHRPIPSVAAPLLVEGADRADLTQITVLPRVRAVGGHNYDILFIGTSDGKVLKVVEVDGNATVIQSATVFQRGVPIVNLLTTKESVVIVSADEIASLPVHNCAQQTSCSKCVQLQDPHCAWDSSIARCVHGGSWTGDQFIQNMVFGQSEQCPEGIIVREVFDDNESEAQPEAVSRSGYPKEHSTITVVLVAAVASLISLIIGAFIGIRVNRWAATSEPHRSASSTSGSDYDSFGRARLTRHDSLTTATKVDHGFVPQSKQSVDATSLVMSINATHHPMSMSQHGSGINTPSRDKNAIVTSINQNTLPRDYKVKKVYL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
75	N-linked (GlcNAc...) asparagine	UniProt
165	N-linked (GlcNAc...) asparagine	UniProt
285	N-linked (GlcNAc...) asparagine	UniProt
346	N-linked (GlcNAc...) asparagine	UniProt
455	N-linked (GlcNAc...) asparagine	UniProt
559	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
CRMPs in Sema3A signaling	Caenorhabditis elegans
Other semaphorin interactions	Caenorhabditis elegans
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	Caenorhabditis elegans
Sema4D induced cell migration and growth-cone collapse	Caenorhabditis elegans

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