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Heat shock protein 90

Summary

UniProt ID

Q18688

Gene Symbol

daf-21

Organism

Caenorhabditis elegans

External Links

PubChem: Q18688
The O-GlcNAc Database: Q18688

Annotation

Keyword

3D-structure
ATP-binding
Cell cycle
Chaperone
Cytoplasm
Direct protein sequencing
Reference proteome
Stress response

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

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GO Term
chemotaxis
cell cycle
regulation of chemotaxis
protein stabilization
chaperone-mediated protein folding
protein maturation by protein folding
cellular response to heat
nematode larval development
protein dephosphorylation
defense response to Gram-negative bacterium

Displaying **all 9** entries
GO Term
protein-containing complex
HSP90-CDC37 chaperone complex
cytosol
membrane raft
cytoplasm
plasma membrane
protein serine/threonine phosphatase complex
protein folding chaperone complex
perinuclear region of cytoplasm

Displaying **all 8** entries
GO Term
ATP binding
disordered domain specific binding
ATP-dependent protein folding chaperone
protein phosphatase 5 binding
nuclear glucocorticoid receptor binding
identical protein binding
unfolded protein binding
ATP hydrolysis activity

Annotation information from UniProt.

Sequence

MSENAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKLVVEKEREKEVEDEEAVEAKDEEKKEGEVENVADDADKKKTKKIKEKYFEDEELNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLRYSTSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLDIGDDEIEDSAVPSSCTAEAKIEGAEEDASRMEEVD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 12 in total

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Pathway Name	Organism
Aryl hydrocarbon receptor signalling	Caenorhabditis elegans
Downregulation of ERBB2 signaling	Caenorhabditis elegans
Drug-mediated inhibition of ERBB2 signaling	Caenorhabditis elegans
Extra-nuclear estrogen signaling	Caenorhabditis elegans
HSF1 activation	Caenorhabditis elegans
HSF1-dependent transactivation	Caenorhabditis elegans
HSP90 chaperone cycle for SHRs	Caenorhabditis elegans
Neutrophil degranulation	Caenorhabditis elegans
Signaling by ERBB2	Caenorhabditis elegans
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	Caenorhabditis elegans

GlyTouCan

GlyComb

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UniCarb-DR

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Summary

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Annotation

International Collaboration

Acknowledgements