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Cadherin-4

Summary

UniProt ID: Q19319
Gene Symbol: F25F2.2 cdh-4
Gene ID: 175590
Organism: Caenorhabditis elegans

External Links

GlycoProtDB: GPDB0000676
Re-Glyco: Q19319

Annotation

Keyword: Calcium Cell adhesion Cell membrane Developmental protein Disulfide bond EGF-like domain Glycoprotein Metal-binding Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
homophilic cell-cell adhesion	IEA	GO_REF
establishment or maintenance of cell polarity	IMP	PMID
establishment or maintenance of cell polarity	IEA	GO_REF
axon guidance	IMP	PMID
axon guidance	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

homophilic cell-cell adhesion

establishment or maintenance of cell polarity

cell motility [inference]

cell migration [inference]

neuroblast migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

Displaying **all 2** entries
GO Term	Evidence Code	Reference
plasma membrane	IEA	GO_REF GO_REF
cell-cell junction	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

Displaying **all 2** entries
GO Term	Evidence Code	Reference
calcium ion binding	IBA	GO_REF
calcium ion binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKKHRVFHLFLLIFCKAISLVTTSSSTEQIFEFTAPLYNLSVEENSIGSKYARSENSTKIGVPLPEKDANCKFRVAEIVGEKSSLFKAHSRQVGDFVFLRIRYKGDNPLNRELKDFYDILVKAMCKRRDLSNLETTARIHLRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINSAIYFSLVNRSHDFIVEPVTGWVRSLRHVKPGKYSLKVKSEDRASRLYYFDENEVQPSWTADVLITVRETKPKPRRILVDQRKINPNILNNRQLAAIITLKDSPNDAIVGLKGNEKEHWFEVEPEVVGNDGTKELRWMLYAKNGSQVPKNTNVTLTIGEDYIRRSGFSISKKPVIPTNETVTIQIERLAEHLIRFLDNEKLTLKTDEMAPIGRILYRMNVNVENPDDVSLIRYSLEYSKSDLPNATLPFAIGSKNGILRVSAKINRSERVYNFKVIASLHGINEKLAEKDVSIEILDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTSELPLEINANTGEITLVEVPKKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQESENKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIHHYSVRSKFAGKLCRIFAVDADEGENARLTYNITEGDARFSIDNNGNIIASEAIHGDESYALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEISGKKSDYVIPISDADQVGLTVGKLEASDADGDELWWSISSGDPDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQAWDHSTVIIQVSRQISQRPKFSASHYQTDVSERVAVGTQIYTLKASGESLGTKPLVFNLFSVDDVAMEDKIRVEPSSGNVIVMEPLDYEAARRIRAVVQVQQANMKSFATFSVNINDENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVRLAKPLDPELQHVESILRIRAIDSAANSLKDEMSLHIRNSNEAPETAKFDRKVYQTTLYDSTRPGTPVLVLNALHHGTVSYKLEPNCTFFEVHTLSGAVHLATWLTKLKHRKSVECTAIVESTEGQQDIAKVIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKDEQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPPRFPSNSLDISMILPTANGVSVGGQTAQDMDSVGSLRYFIKDQSVPFSVDSKTGDVLVKDSNGISDMTKLFDLEVFVTDGKQSASYVMKISTISTENSKFKFTRNEYHTSLIENTTLPPGSIILSVATIGDKLDHFSIVNPHEAFFIHPGTGVISSSGIALDREKSAIIRLVVQAKSHEKNPVMARALVVVGIENINDETPIFMGTPYDITIGHSDIGTVVLEPKVIDNDEGDVVTISSENMPEYFKIVGGKVVLGKKLPSIEEEDLEFNFKLIAKDNGSVHRVEEPVKIRVVDKARPVFSQNVYTAVISKESTKKSTVLVKVMAKSSLQSKSKGLIGYRILDKKSPFSVDFLTGEVRLNNLKMLAETNYTFEVEAREVTRPKMIAKAQVEIIVKSGITTHAPVFEKLKYTASTPESTSIGQRLLTIKATTSDENDTIEYSLSGSKDIEIHPETGDVTITGQLDYEKTQKYDLKLVATSSGKQVSSEAEFIVLIEDVNDEMPEFIRSDVSAKISDSAITGQFITIMSATDMDTTNSLDEESQKLLYKIVDGDETLFNISPATGELSLARPVEQDDLVNEDTKKVLNVSVTDGMFTAYAKLVVEILRSGSMQPPPRFEQSHYVANALENTIVNKSALLTVAVKGGVPPLQFSLAPTTSSNSSTSKEAWPVAIDRKTGRIHVSRVLNYHRDKRYQIPLVVEDATGRRAFSTLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDENDTIEYSLLDGSESQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRADAAGGVHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEENPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDLHLPSTSPILHFSIKDDDLSPNNVSQFFIPKGNEEGVFWIDSNNDLLLKRPEIVENKMQYQLKVTAFDGVFETSTKVKINLKSSKDSDIRCPEANKTVILAENSKKGTVVLGESSLLGPNVTFKLSDNDGNVFVVNFRNGIVKVKESDQIDYEKNQQLEFHRLTIQDNSEVCKELITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDEIKFRMVDDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVASDGEFEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLDGPKNGAPFTVEIQGDGAKSFKVNEKLELLTAKKLEYRKKDKYLLTVIAKDVKGKTTDCPLTIFIRQTSRHAPTMKPMKIQINTLQNELPEGIIGRLKASDEDEEDQNGLLRFGLVEGSIQSPRAQVQESRSTHLFRVDPNTGDIWSDHSITQGLHTFNVTVTDSKFNTVSYVEVHVTSIDNDVIDHAVSIRIRSMSVDEFMRKHVKEFRRIISHHLNLNDDSSIQLISVQAVPSTESERRSRRNSMEDVEILMTAQRGLGRGYLKPDHIYSRLKNDFQNMNDQSQRMRYQLITEMCTTGVCLRGECREVIELIEDSWTKVSTDDFSFVSPFHSRSAQCLCPDGFGGKRCEVETNQCAKSPCEQWQLCIPSVHNSTYECVCPLGMEGDKCSVPSCQNDGKCLEEAELSVGGDGYFEISLSNEIETRMELEIELKTTTHNGIIMWSRGKRDFHMLRLVNGTPEYHWNAGTGTGIVTSKTSVVDGQWHRIAISRRQRRTRMTVDDEDLQEAFSPIGSTVINLHRYSQKLVLGAKVDDGELTDGVSACFRTISVDGMKVLKTRQGMKLFGAQPGCSALTSSPCNDLPCQHAGTCISQGKSHFKCECPSRYSGNVCEIDLEPCASSPCPTGIQCIPFYNDYLCKCPNGFTGKHCEARGFEDHETSSCSKNVCGTSGQCISIPRHSLESSDFICNCTGGILQSTPCAEKSDILSTVLEFLLKAEIVIVILGVLLLLLVFCLTFITWKCCKKNRDPKYGAHCDVPHMRNTRVLVPVVPPPLPPRGFRNDSSNFISTSSVTTSHRPMVQVKPYSSDIRDSRSPSACGSSKGTRRDPLPSDKFRRVDETANRIRHSDRKDPRGDVLSSLRDSSDEWMGIDDRIDSSLKYSRAAAGTVIVGDTELMPVINDNDYMTMKPRKDKNFEREKPPAIPAHATPLESVLKLGSSSSGEEAPRNALYDDPISLDSQTFDDIDEEVNIHIS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 32 in total

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Position	Description	Source
39	N-linked (GlcNAc...) asparagine	UniProt
56	N-linked (GlcNAc...) asparagine	UniProt
196	N-linked (GlcNAc...) asparagine	UniProt
330	N-linked (GlcNAc...) asparagine	UniProt
339	N-linked (GlcNAc...) asparagine	UniProt
365	N-linked (GlcNAc...) asparagine	UniProt
431	N-linked (GlcNAc...) asparagine	UniProt
452	N-linked (GlcNAc...) asparagine	UniProt
584	N-linked (GlcNAc...) asparagine	UniProt
811	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Formation of the cornified envelope	Caenorhabditis elegans
Neutrophil degranulation	Caenorhabditis elegans
RAC3 GTPase cycle	Caenorhabditis elegans

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements