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MIRAGE

RNA helicase

Summary

UniProt ID: Q22308
Gene Symbol: ddx-19 CELE_T07D4.4 T07D4.4
Gene ID: 174418
Organism: Caenorhabditis elegans

External Links

The O-GlcNAc Database: Q22308
Re-Glyco: Q22308

Annotation

Keyword: Helicase Proteomics identification RNA-binding Reference proteome

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	Reference
germ cell development	IGI	PMID
poly(A)+ mRNA export from nucleus

GO Hierarchy

biological process

cellular process [inference]

intercellular transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

cellular developmental process [inference]

cell development [inference]

germ cell development

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development

multicellular organismal reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development

anatomical structure development [inference]

cell development [inference]

germ cell development

cellular developmental process [inference]

cell development [inference]

germ cell development

localization [inference]

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

Displaying **all 3** entries
GO Term	Evidence Code	Reference
nucleus
cytoplasmic stress granule	IBA	GO_REF
P granule	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

Displaying **all 4** entries
GO Term	Evidence Code	Reference
RNA helicase activity	IEA	GO_REF GO_REF
mRNA binding
ATP binding	IEA	GO_REF GO_REF
hydrolase activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

nucleic acid conformation isomerase activity [inference]

helicase activity [inference]

RNA helicase activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity [inference]

RNA helicase activity

catalytic activity, acting on RNA [inference]

RNA helicase activity

binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

helicase activity [inference]

RNA helicase activity

ATP-dependent activity, acting on RNA [inference]

RNA helicase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MADWGIAFDEQCRSEGLEVPEKTEKVQSGSEMDQNEENKGSNGWGISRGGMFGGPKASNAPPPQTSFGSTSGTRVGGSFGGQAGVDGRGAPLGSAEELIGGGNIISVGIHKEKPACKRGGGFGTNRSMAPCPPAIIKNNHEGGRFGVLAPRTLSGSIPQTSTNLEDSTPKTSTGGRFGASISQGGAFGAKTQSSSVAPSVGGGFGVKSPNIVSNDMPKVPVMKSVGGGFGSSMKSPATTGGSFGSSTVVASIRSEESFGIKSSASAGGSFNSSSASASQSRTVASFGSKPSNENISSNSSALSSSSSCFAAKPTSTSAGGSFGNQPSSFSSKPSFGGAFGASTSVTGSSSMGGSFGNKSTKVPDVESLSPPEILRNPSNTSGGAFGSKPSFAASSSELPANKHVVGGGFGRSTAPTVNTSVGNESGRLPFVETRNPNTEQETSSSVRPYGANFNSKSEPAQKNPFGGNSSSTKPEFKENEMKNSSVPIMPGQSQPMRGGFQGAYRGGRGSGGGQMDFGAPGQGQSMGRGRGQQNPAFVPRPRDTPPQYGGHQAAQQFVKPDSKYKFTKPATEEAHEQVPVPADIALLNKFIQKEVKMMKDVVVDVQRQDPKSPLYSISSFRELRLKPEVLKALDTMNFQFPTRIQETALPLLLMEPPSNLIAQAQSGTGKTAAFVLTMLCRIDVNLMCPQCICLAPTLELAKQIGEVVEKMGKFIDNLKIHYAIKGGNMAAMRGRKLTEQIVIGTPGITRDYLQKYKCIDPSKIRCLVLDEADVMIYHQGFTDISTTIYNMVEDASDSVQSMLFSATYDEPVINFATKIIKNAIVVMLKREEQALPNIKQFYVQCACRDSKYAAIVNLYSGLAVASSVIFCHTKASVMWLYENMRARGHQVDVLHGDMTVVERADTIIHFKRGDFKVLITTNVFARGIDVAQVSVVINYDLPIKYTDEGTPMVVDGFTQPDCETYLHRIGRTGRFGKTGIAINLIDSEDSMNMINVLENHFQMKIARMDPSNLVELEAIEMA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
152		31682414	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026