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Lachesin

Summary

UniProt ID

Q24372

Gene Symbol

CG12369
Lac

Gene ID

[36363]

Organism

Drosophila melanogaster (fruit fly)

External Links

Re-Glyco: Q24372

Annotation

Keyword: Cell adhesion Cell membrane Developmental protein Disulfide bond GPI-anchor Immunoglobulin domain Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
homophilic cell-cell adhesion	IDA	PMID
open tracheal system development	IEP	PMID
open tracheal system development	IMP	PMID PMID PMID
morphogenesis of embryonic epithelium	IMP	PMID
septate junction assembly	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell adhesion involved in heart morphogenesis

cell-cell adhesion [inference]

homophilic cell-cell adhesion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

tight junction organization [inference]

tight junction assembly [inference]

septate junction assembly

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of epithelial integrity, open tracheal system

developmental process [inference]

anatomical structure morphogenesis [inference]

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of embryonic epithelium

anatomical structure development [inference]

system development [inference]

respiratory system development [inference]

open tracheal system development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of epithelial integrity, open tracheal system

biological regulation [inference]

regulation of biological quality [inference]

regulation of tube architecture, open tracheal system [inference]

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube size, open tracheal system

Displaying **all 5** entries
GO Term	Evidence Code	Reference
plasma membrane	IEA	GO_REF
plasma membrane	HDA	PMID PMID
septate junction	IDA	PMID
neuron projection	IBA	GO_REF
side of membrane

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

septate junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

side of membrane

Displaying 1 entry
GO Term	Evidence Code	Reference
protein homodimerization activity	IDA	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MWRPSISNCVWSTLLLAIFVQQTLAQRTPTISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCPPACGQAYIAGAEDVSATSFALVGILAALLFAR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
92	N-linked (GlcNAc...) asparagine			UniProt
140	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 13 in total

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Pathway Name	Organism
Degradation of the extracellular matrix	Drosophila melanogaster
ECM proteoglycans	Drosophila melanogaster
Formation of the dystrophin-glycoprotein complex (DGC)	Drosophila melanogaster
Glycosaminoglycan-protein linkage region biosynthesis	Drosophila melanogaster
HS-GAG biosynthesis	Drosophila melanogaster
HS-GAG degradation	Drosophila melanogaster
Integrin cell surface interactions	Drosophila melanogaster
NCAM signaling for neurite out-growth	Drosophila melanogaster
NCAM1 interactions	Drosophila melanogaster
Non-integrin membrane-ECM interactions	Drosophila melanogaster

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements